Autologous keratinocyte cultures and combinations of scaffolds, different cell types, solutions
of macromolecules, or growth factors have contributed to the resurfacing of burns and large …

Defensins are small, multifunctional cationic peptides. They typically contain six conserved
cysteines whose three intramolecular disulfides stabilize a largely β‐sheet structure. This …

Following the “finished,” euchromatic, haploid human reference genome sequence, the
rapid development of novel, faster, and cheaper sequencing technologies is making …

DNA copy number variation has long been associated with specific chromosomal
rearrangements and genomic disorders, but its ubiquity in mammalian genomes was not …

Copy number variants (CNVs) are among the largest genetic variants, yet CNVs have not
been effectively ascertained in most genetic association studies. Here we ascertained …

Psoriasis is a common inflammatory skin disease with a strong genetic component. We
analyzed the genomic copy number polymorphism of the β-defensin region on human …

Defensins are small antimicrobial peptides that are produced by leukocytes and epithelial
cells, and that have an important role in innate immunity. Recent advances in understanding …

Copy number variation (CNV) has recently gained considerable interest as a source of
genetic variation likely to play a role in phenotypic diversity and evolution. Much effort has …

IgA nephropathy (IgAN) represents the leading cause of kidney failure among East Asian
populations and the most frequent form of primary glomerulonephritis among Europeans …

α, β, and θ defensins are effectors of the innate immune system with potent antibacterial,
antiviral, and antifungal activity. Defensins have direct antiviral activity in cell culture, with …