Cellular fusion eg between cancer cells and normal cells represents a stepwise process that
is tightly regulated. During a pre-hybrid preparation program somatic cells and/or cancer …

The dual functions of TMEM16F as Ca2+-activated ion channel and lipid scramblase raise
intriguing questions regarding their molecular basis. Intrigued by the ability of the FDA …

The virulence of SARS-CoV-2 decreases with increasing infectivity, the primary approaches
for antiviral treatments will be preventing or minimizing the complications resulting from virus …

Abstract The Ca2+ activated Cl− channel TMEM16A (anoctamin 1; ANO1) is expressed in
secretory epithelial cells of airways and intestine. Previous studies provided evidence for a …

The calcium-activated TMEM16 proteins and the mechanosensitive/osmolarity-activated
OSCA/TMEM63 proteins belong to the Transmembrane Channel/Scramblase (TCS) …

Aqueous humor drainage from the anterior eye determines intraocular pressure (IOP) under
homeostatic and pathological conditions. Swelling of the trabecular meshwork (TM) alters its …

ABSTRACT TMEM16F (also known as ANO6), a Ca2+-activated lipid scramblase
(CaPLSase) that dynamically disrupts lipid asymmetry, plays a crucial role in various …

Cell-surface exposure of phosphatidylserine (PS) is essential for phagocytic clearance and
blood clotting. Although a calcium-activated phospholipid scramblase (CaPLSase) has long …

Angiogenesis has been considered a pivotal strategy for treating ischemic heart disease.
One possible approach, the Shexiang Baoxin Pill (MUSKARDIA), has been noted to …

The placenta is an important organ for the exchange of substances between the fetus and
the mother, hormone secretion, and fetoplacental immunological defense. Placenta has an …