Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

VSMC s in resistance arteries and arterioles express a diverse array of KV channels with
members of the KV 1, KV 2 and KV 7 families being particularly important. Members of the …

Potassium channels importantly contribute to the regulation of vascular smooth muscle
(VSM) contraction and growth. They are the dominant ion conductance of the VSM cell …

Potassium (K+) ion channel activity is an important determinant of vascular tone by
regulating cell membrane potential (MP). Activation of K+ channels leads to membrane …

Of the 21 members of the connexin family, 4 (Cx37, Cx40, Cx43, and Cx45) are expressed in
the endothelium and/or smooth muscle of intact blood vessels to a variable and dynamically …

Biological tissues are fed by arterial networks whose task is to set blood flow delivery in
accordance with energetic demand. Coordinating vasomotor activity among hundreds of …

Vascular resistance networks control tissue blood flow in concert with regulating arterial
perfusion pressure. In response to increased metabolic demand, vasodilation arising in …

Vascular endothelial cells, as well as smooth muscle cells, show heterogeneity with regard
to their receptor expression and reactivity. For the vascular wall to act as a functional unit …

The conducted vasomotor response reflects electrical communication in the arterial wall and
the distance signals spread is regulated by three factors including resident ion channels …

Irisin, an exercise-induced myokine, has been shown to have a peripheral vasodilator effect.
However, little is known about the mechanisms underlying its effects. In this study, it was …