Effects of statins on mitochondrial pathways

H Mollazadeh, E Tavana, G Fanni, S Bo… - Journal of Cachexia …, 2021 - Wiley Online Library
Statins are a family of drugs that are used for treating hyperlipidaemia with a recognized
capacity to prevent cardiovascular disease events. They inhibit β‐hydroxy β‐methylglutaryl …

Metabolic targets for cancer therapy

L Galluzzi, O Kepp, MGV Heiden… - Nature reviews Drug …, 2013 - nature.com
Malignant cells exhibit metabolic changes, when compared to their normal counterparts,
owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has …

From race-based to race-conscious medicine: how anti-racist uprisings call us to act

JP Cerdeña, MV Plaisime, J Tsai - The Lancet, 2020 - thelancet.com
The brutalisation of Jacob Blake and murders of George Floyd, Breonna Taylor, Ahmaud
Arbery, Tony McDade, and countless others—coupled with horrifying statistics about the …

Statin-related myotoxicity: a comprehensive review of pharmacokinetic, pharmacogenomic and muscle components

RM Turner, M Pirmohamed - Journal of clinical medicine, 2019 - mdpi.com
Statins are a cornerstone in the pharmacological prevention of cardiovascular disease.
Although generally well tolerated, a small subset of patients experience statin-related …

Statins neuromuscular adverse effects

S Attardo, O Musumeci, D Velardo… - International journal of …, 2022 - mdpi.com
Statins are drugs widely prescribed in high-risk patients for cerebrovascular or
cardiovascular diseases and are, usually, safe and well tolerated. However, these drugs …

Statin intolerance–an attempt at a unified definition. Position paper from an International Lipid Expert Panel: This paper is also published in parallel in Archives of …

M Banach, M Rizzo, PP Toth, M Farnier… - Expert opinion on …, 2015 - Taylor & Francis
Statins are one of the most commonly prescribed drugs in clinical practice. They are usually
well tolerated and effectively prevent cardiovascular events. Most adverse effects associated …

Understanding Statin Use in America and Gaps in Patient Education (USAGE): an internet-based survey of 10,138 current and former statin users

JD Cohen, EA Brinton, MK Ito, TA Jacobson - Journal of clinical lipidology, 2012 - Elsevier
BACKGROUND: Statins substantially reduce the risk of cardiovascular disease and are
generally well-tolerated. Despite this, many patients discontinue therapy. A better …

The role of statins in both cognitive impairment and protection against dementia: a tale of two mechanisms

BG Schultz, DK Patten, DJ Berlau - Translational neurodegeneration, 2018 - Springer
Nearly 30% of adults 40 years and older in the United States are on a statin. Their
widespread use heightens the importance of careful consideration of their varied effects on …

Preparation of a carboxymethylcellulose-iron composite for uptake of atorvastatin in water

I Ali, OML Alharbi, ZA ALOthman, A Alwarthan… - International Journal of …, 2019 - Elsevier
Many water bodies are being contaminated by atorvastatin, which has certain side effects
and problems on healthy individuals through contaminated water. For this purpose, effective …

[HTML][HTML] Garlic lowers blood pressure in hypertensive individuals, regulates serum cholesterol, and stimulates immunity: an updated meta-analysis and review

K Ried - The Journal of nutrition, 2016 - Elsevier
Background: Garlic has been shown to have cardiovascular protective and
immunomodulatory properties. Objectives: We updated a previous meta-analysis on the …