Neurosarcoidosis: pathophysiology, diagnosis, and treatment

MJ Bradshaw, S Pawate, LL Koth, TA Cho… - Neurology …, 2021 - AAN Enterprises
Although often regarded as a protean illness with myriad clinical and imaging
manifestations, neurosarcoidosis typically presents as recognizable syndromes that can be …

Classical examples of the concept of the ASIA syndrome

V Borba, A Malkova, N Basantsova, G Halpert… - Biomolecules, 2020 - mdpi.com
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) was first introduced in
2011 by Shoenfeld et al. and encompasses a cluster of related immune mediated diseases …

Infliximab for the treatment of CNS sarcoidosis: a multi-institutional series

JM Gelfand, MJ Bradshaw, BJ Stern, DB Clifford… - Neurology, 2017 - AAN Enterprises
Objective: To describe clinical and imaging responses in neurosarcoidosis to infliximab, a
monoclonal antibody against tumor necrosis factor–α. Methods: Investigators at 6 US …

Sarcoidosis as an autoimmune disease

AA Starshinova, AM Malkova, NY Basantsova… - Frontiers in …, 2020 - frontiersin.org
Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis
still remain unknown. Most researchers allude to the possible autoimmune or immune …

Cutaneous sarcoidosis

A Caplan, M Rosenbach… - Seminars in Respiratory …, 2020 - thieme-connect.com
Sarcoidosis is a chronic, multisystem, inflammatory disorder of unknown etiology that is
characterized by noncaseating granulomas that impair normal organ functioning …

Cutaneous sarcoidosis

KA Wanat, M Rosenbach - Clinics in chest medicine, 2015 - chestmed.theclinics.com
Sarcoidosis is a multisystem, noncaseating granulomatous disorder of unknown cause with
skin as the second most common organ affected, occurring in 25% to 30% of cases reported …

Microbial lineages in sarcoidosis. A metagenomic analysis tailored for low–microbial content samples

EL Clarke, AP Lauder, CE Hofstaedter… - American journal of …, 2018 - atsjournals.org
Rationale: The etiology of sarcoidosis is unknown, but microbial agents are suspected as
triggers. Objectives: We sought to identify bacterial, fungal, or viral lineages in specimens …

Histomorphological patterns of regional lymph nodes in COVID-19 lungs

JD Haslbauer, MS Matter, AK Stalder, A Tzankov - Der Pathologe, 2021 - Springer
Background A dysregulated immune response is considered one of the major factors
leading to severe COVID-19. Previously described mechanisms include the development of …

Next-generation sequencing based HLA typing: deciphering immunogenetic aspects of sarcoidosis

A Kishore, M Petrek - Frontiers in genetics, 2018 - frontiersin.org
Unraveling of the HLA-related immunogenetic basis of several immune disorders is complex
due to the extensive HLA polymorphism and strong linkage-disequilibrium between HLA …

New concepts in the pathogenesis of sarcoidosis

D Bennett, E Bargagli, RM Refini… - Expert Review of …, 2019 - Taylor & Francis
Introduction: The pathogenesis of sarcoidosis is not yet completely understood, although in
recent years our knowledge has made considerable progress. Areas covered: This review …