[HTML][HTML] RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
[HTML][HTML] Global positioning system: understanding long noncoding RNAs through subcellular localization
J Carlevaro-Fita, R Johnson - Molecular cell, 2019 - cell.com
The localization of long noncoding RNAs (lncRNAs) within the cell is the primary
determinant of their molecular functions. LncRNAs are often thought of as chromatin …
determinant of their molecular functions. LncRNAs are often thought of as chromatin …
[HTML][HTML] Reassessment of exosome composition
The heterogeneity of small extracellular vesicles and presence of non-vesicular extracellular
matter have led to debate about contents and functional properties of exosomes. Here, we …
matter have led to debate about contents and functional properties of exosomes. Here, we …
Obstacles and opportunities in the functional analysis of extracellular vesicle RNA–an ISEV position paper
The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body …
been demonstrated in a multitude of different in vitro cell systems and in a variety of body …
[HTML][HTML] Coding and noncoding landscape of extracellular RNA released by human glioma stem cells
Tumor-released RNA may mediate intercellular communication and serve as biomarkers.
Here we develop a protocol enabling quantitative, minimally biased analysis of extracellular …
Here we develop a protocol enabling quantitative, minimally biased analysis of extracellular …
[HTML][HTML] exRNA atlas analysis reveals distinct extracellular RNA cargo types and their carriers present across human biofluids
To develop a map of cell-cell communication mediated by extracellular RNA (exRNA), the
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource …
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource …
Broad role for YBX1 in defining the small noncoding RNA composition of exosomes
RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA
composition of EVs is challenging due to their coisolation with contaminants, lack of …
composition of EVs is challenging due to their coisolation with contaminants, lack of …
[HTML][HTML] Large differences in small RNA composition between human biofluids
PM Godoy, NR Bhakta, AJ Barczak, H Cakmak… - Cell reports, 2018 - cell.com
Extracellular microRNAs (miRNAs) and other small RNAs are implicated in cellular
communication and may be useful as disease biomarkers. We systematically compared …
communication and may be useful as disease biomarkers. We systematically compared …
[HTML][HTML] Extracellular vesicles in physiology, pathology, and therapy of the immune and central nervous system, with focus on extracellular vesicles derived from …
S Koniusz, A Andrzejewska, M Muraca… - Frontiers in cellular …, 2016 - frontiersin.org
Extracellular vesicles (EVs) are membrane-surrounded structures released by most cell
types. They are characterized by a specific set of proteins, lipids and nucleic acids. EVs have …
types. They are characterized by a specific set of proteins, lipids and nucleic acids. EVs have …
GraphLncLoc: long non-coding RNA subcellular localization prediction using graph convolutional networks based on sequence to graph transformation
The subcellular localization of long non-coding RNAs (lncRNAs) is crucial for understanding
lncRNA functions. Most of existing lncRNA subcellular localization prediction methods use k …
lncRNA functions. Most of existing lncRNA subcellular localization prediction methods use k …