Screening embryos for polygenic disease risk: a review of epidemiological, clinical, and ethical considerations
A Capalbo, G de Wert, H Mertes… - Human reproduction …, 2024 - academic.oup.com
BACKGROUND The genetic composition of embryos generated by in vitro fertilization (IVF)
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …
Ready for polygenic risk scores? An analysis of regulation of preimplantation genetic testing in European countries
M Siermann, V van der Schoot, EM Bunnik… - Human …, 2024 - academic.oup.com
STUDY QUESTION Would the different regulatory approaches for preimplantation genetic
testing (PGT) in Europe permit the implementation of preimplantation genetic testing using …
testing (PGT) in Europe permit the implementation of preimplantation genetic testing using …
Perspectives of preimplantation genetic testing patients in Belgium on the ethics of polygenic embryo screening
M Siermann, JR Vermeesch, T Raivio, A Vanhie… - Reproductive …, 2024 - Elsevier
Research question What are the perspectives of preimplantation genetic testing patients in
Belgium on the ethics of preimplantation genetic testing for polygenic risk scoring (PGT-P) …
Belgium on the ethics of preimplantation genetic testing for polygenic risk scoring (PGT-P) …
Polygenic embryo screening: quo vadis?
M Siermann, JR Vermeesch, T Raivio, O Tšuiko… - Journal of Assisted …, 2024 - Springer
Recently, the use of polygenic risk scores in embryo screening (PGT-P) has been introduced
on the premise of reducing polygenic disease risk through embryo selection. However, it has …
on the premise of reducing polygenic disease risk through embryo selection. However, it has …