ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

Iron is essential for many biological functions in bacteria, but its poor solubility is a limiting
factor for growth. Bacteria produce siderophores, soluble natural products that bind iron with …

Siderophores are iron-chelating molecules that solubilize Fe 3+ for microbial utilization and
facilitate colonization or infection of eukaryotes by liberating host iron for bacterial uptake. By …

We studied the Escherichia coli outer membrane protein Fiu, a presumed transporter of
monomeric ferric catecholates, by introducing Cys residues in its surface loops and …

Microbes synthesize and secrete siderophores, that bind and solubilize precipitated or
otherwise unavailable iron in their microenvironments. Gram (−) bacterial TonB-dependent …

The Escherichia coli outer membrane receptor FepA transports ferric enterobactin (FeEnt) by
an energy-and TonB-dependent, but otherwise a mechanistically undetermined process …

Membrane transporters and soluble binding proteins recognize particular nutrients,
metabolites, vitamins, or ligands. By modifying genetically engineered single cysteine …

ABSTRACT The TonB system of Escherichia coli uses the cytoplasmic membrane
protonmotive force (PMF) to energize active transport of nutrients across the otherwise …

The increasing antibiotic resistance of Gram-negative bacteria, eg, Enterococcus,
Staphylococcus, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter (ESKAPE) …