Marine organisms represent a valuable source of new compounds. The biodiversity of the
marine environment and the associated chemical diversity constitute a practically unlimited …

More than 32 species of sea anemones have been reported to produce lethal cytolytic
peptides and proteins. Based on their primary structure and functional properties, cytolysins …

Abstract Sticholysin I and II (St I and St II), two basic cytolysins purified from the Caribbean
sea anemone Stichodactyla helianthus, efficiently permeabilize lipid vesicles by forming …

Actinoporins are effective pore-forming toxins produced by sea anemones. These extremely
potent, basic 20kDa proteins readily form pores in membranes that contain sphingomyelin …

Sticholysins (Sts) I and II (StI/II) are pore-forming toxins (PFTs) produced by the Caribbean
Sea anemone Stichodactyla helianthus belonging to the actinoporin family, a unique class …

Sea anemones produce a family of 18–20 kDa proteins, the actinoporins, that lyse cells by
forming pores in cell membranes. Sphingomyelin plays an important role in their lytic activity …

The radius of the pore formed by sticholysin I and II (StI, StII) in erythrocytes and sticholysin I
in lipid vesicles was investigated. The rate of colloid osmotic lysis of human erythrocytes …

Sea anemones are an important source of various biologically active peptides, and it is
known that ATX-II from Anemonia sulcata slows sodium current inactivation. Using six …

Pore-forming toxins (PFTs) form holes in membranes causing one of the most catastrophic
damages to a target cell. Target organisms have evolved a regulated response against PFTs …

Sea anemone toxins are predominantly peptide and proteins that act mainly on sodium and
potassium channels, as well as in a variety of target cells causing lysis. Over recent years …