Ultrasonic apparatus for thermotherapy with variable frequency for suppressing cavitation

K Fujimoto, Y Ishibashi, M Shibata, T Suzuki… - US Patent …, 1997 - Google Patents
An ultrasonic diagnosis apparatus for raising tissue temperature for hypothermic treatments,
including an ultrasonic source for generating an ultrasonic treatment wave and a driving …

Therapeutic drug delivery systems

EC Unger, TA Fritz, T Matsunaga… - US Patent …, 1996 - Google Patents
Therapeutic drug delivery systems comprising gas-? lled microspheres comprising a
therapeutic are described. Meth ods for employing such microspheres in therapeutic drug …

Charged lipids and uses for the same

EC Unger - US Patent 6,120,751, 2000 - Google Patents
PORPENFLTBBHSG-MGBGTMOVSA-N 1, 2-dihexadecanoyl-sn-glycerol-3-phosphate
Chemical compound CCCCCCCCCCCCCCCC (= O) OC [C@ H](COP (O)(O)= O) OC (= O) …

Endoluminal implant with therapeutic and diagnostic capability

GW Keilman, GE Cimochowski - US Patent 6,231,516, 2001 - Google Patents
In the 1970s, the technique of percutaneous transluminal coronary angioplasty (PTCA) was
developed for the treat ment of atherOSclerosis. Atherosclerosis is the build-up of fatty …

Implantable therapeutic device and method

GW Keilman, GE Cimochowski - US Patent 6,585,763, 2003 - Google Patents
US6585763B1 - Implantable therapeutic device and method - Google Patents
US6585763B1 - Implantable therapeutic device and method - Google Patents Implantable …

Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles

EC Unger, TO Matsunaga, D Yellowhair - US Patent 5,733,572, 1998 - Google Patents
This application is a continuation-in-part of application US Ser. No. 159,674,? led Nov. 30,
1993 now abandoned, which in turn is a continuation-in-part of applications US Ser. No …

Targeted gas and gaseous precursor-filled liposomes

EC Unger, TA Fritz, T Matsunaga… - US Patent …, 2000 - Google Patents
Methods of and apparatus for preparing temperature acti vated gaseous precursor-? lled
liposomes are described. Gas eous precursor-? lled liposomes prepared by these methods …

Methods for providing localized therapeutic heat to biological tissues and fluids

EC Unger - US Patent 5,149,319, 1992 - Google Patents
Mackiewicz & Norris 57 ABSTRACT Gas, gaseous precursors and prefluorocarbons are
pres ented as novel potentiators for ultrasonic hyperthermia. The gas, gaseous precursors …

Pulsed cavitational ultrasound therapy

CA Cain, Z Xu, JB Fowlkes, TL Hall… - US Patent …, 2011 - Google Patents
Therapy methods using pulsed cavitational ultrasound therapy can include the
subprocesses of initiation, maintenance, therapy, and feedback of the histotripsy process …

Methods of preparing gas-filled liposomes

EC Unger, TA Fritz, T Matsunaga… - US Patent …, 1995 - Google Patents
[54] METHODS OF PREPARING GAS-FILLED 0458745A1 11/1991 European Pat. 01f..
LIPOSOMES 0314764Bl 9/1992 European Pat. 01f.. O554213A1 8/1993 European Pat …