Melt extrusion with poorly soluble drugs–An integrated review
Over the last few decades, hot melt extrusion (HME) has emerged as a successful
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …
Integrated continuous pharmaceutical technologies—a review
Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …
and development of new active compounds; meanwhile, the structure of the production …
Matrix systems for oral drug delivery: Formulations and drug release
In this current article matrix formulations for oral drug delivery are reviewed. Conventional
dosage forms and novel applications such as 3D printed matrices and aerogel matrices are …
dosage forms and novel applications such as 3D printed matrices and aerogel matrices are …
Quality considerations on the pharmaceutical applications of fused deposition modeling 3D printing
A Melocchi, F Briatico-Vangosa, M Uboldi… - International Journal of …, 2021 - Elsevier
Abstract 3D printing, and particularly fused deposition modeling (FDM), has rapidly brought
the possibility of personalizing drug therapies to the forefront of pharmaceutical research …
the possibility of personalizing drug therapies to the forefront of pharmaceutical research …
[HTML][HTML] Development of immediate release 3D-printed dosage forms for a poorly water-soluble drug by fused deposition modeling: Study of morphology, solid state …
M Fanous, M Bitar, S Gold, A Sobczuk, S Hirsch… - International Journal of …, 2021 - Elsevier
Abstract 3D-printing technologies such as Fused Deposition Modeling (FDM) bring a unique
opportunity for personalized and flexible near-patient production of pharmaceuticals …
opportunity for personalized and flexible near-patient production of pharmaceuticals …
Tailoring immediate release FDM 3D printed tablets using a quality by design (QbD) approach
YM Than, V Titapiwatanakun - International Journal of Pharmaceutics, 2021 - Elsevier
The aims of this work were to produce immediate release printed tablets using fused
deposition modelling (FDM) technique and to systematically explore the effects of different …
deposition modelling (FDM) technique and to systematically explore the effects of different …
Development of immediate release (IR) 3D-printed oral dosage forms with focus on industrial relevance
M Fanous, S Gold, S Hirsch, J Ogorka… - European Journal of …, 2020 - Elsevier
Pharmaceutical 3D-printing represents a potentially new dosing and manufacturing
approach for the pharmaceutical industry, with unique opportunities for personalization of …
approach for the pharmaceutical industry, with unique opportunities for personalization of …
Design and commercialization of an end-to-end continuous pharmaceutical production process: a pilot plant case study
CJ Testa, C Hu, K Shvedova, W Wu… - … Process Research & …, 2020 - ACS Publications
The pharmaceutical industry faces multiple challenges (eg, inefficient manufacturing
techniques, quality control issues, and supply chain vulnerabilities) because of its current …
techniques, quality control issues, and supply chain vulnerabilities) because of its current …
Chronotherapeutic drug delivery of ketoprofen and ibuprofen for improved treatment of early morning stiffness in arthritis using hot-melt extrusion technology
This work developed a chronotherapeutic drug delivery system (CTDDS) utilizing a potential
continuous hot-melt extrusion (HME) technique. Ketoprofen (KTP) and ibuprofen (IBU) were …
continuous hot-melt extrusion (HME) technique. Ketoprofen (KTP) and ibuprofen (IBU) were …
Eutectic mixture and amorphous solid dispersion: Two different supersaturating drug delivery system strategies to improve griseofulvin release using saccharin
This study evaluated the ability of different sweeteners to improve dissolution and to form
and stabilize supersaturated solutions of griseofulvin (GSF), comparing a eutectic mixture …
and stabilize supersaturated solutions of griseofulvin (GSF), comparing a eutectic mixture …