Fingering instability accelerates population growth of a proliferating cell collective
Y Ye, J Lin - Physical Review Letters, 2024 - APS
During the growth of a cell collective, such as proliferating microbial colonies and epithelial
tissues, the local cell growth increases the local pressure, which in turn suppresses cell …
tissues, the local cell growth increases the local pressure, which in turn suppresses cell …
Cellular sensing governs the stability of chemotactic fronts
In contexts ranging from embryonic development to bacterial ecology, cell populations
migrate chemotactically along self-generated chemical gradients, often forming a …
migrate chemotactically along self-generated chemical gradients, often forming a …
Active transport in complex environments
A key feature of many living systems, such as bacteria and eukaryotic cells, is their ability to
actively self-propel. Indeed, cellular motility underlies numerous critical biological …
actively self-propel. Indeed, cellular motility underlies numerous critical biological …
Fingering instability of active nematic droplets
R Alert - Journal of Physics A: Mathematical and Theoretical, 2022 - iopscience.iop.org
From the mitotic spindle up to tissues and biofilms, many biological systems behave as
active droplets, which often break symmetry and change shape spontaneously. Here, I show …
active droplets, which often break symmetry and change shape spontaneously. Here, I show …
The analytical solution to the migration of an epithelial monolayer with a circular spreading front and its implications in the gap closure process
The coordinated behaviors of epithelial cells are widely observed in tissue development,
such as re-epithelialization, tumor growth, and morphogenesis. In these processes, cells …
such as re-epithelialization, tumor growth, and morphogenesis. In these processes, cells …
Bifurcation of finger-like structures in traveling waves of epithelial tissues spreading
We consider a continuous active polar fluid model for the spreading of epithelial monolayers
introduced by R. Alert, C. Blanch-Mercader, and J. Casademunt, 2019. The corresponding …
introduced by R. Alert, C. Blanch-Mercader, and J. Casademunt, 2019. The corresponding …
Modeling growing confluent tissues using a lattice Boltzmann method: Interface stability and fluctuations
Tissue growth underpins a wide array of biological and developmental processes, and
numerical modeling of growing systems has been shown to be a useful tool for …
numerical modeling of growing systems has been shown to be a useful tool for …
Dynamics and instabilities of the free boundary of a two-dimensional dry active nematic aggregate
LS Lin, HY Chen - Journal of Physics Communications, 2021 - iopscience.iop.org
The dynamics of a two-dimensional aggregate of active rod-shaped particles in the nematic
phase with a free boundary is considered theoretically. The aggregate is in contact with a …
phase with a free boundary is considered theoretically. The aggregate is in contact with a …
Fingering instability accelerates population growth of an expanding cell collective
Y Ye, J Lin - bioRxiv, 2023 - biorxiv.org
During the expansion of a cell collective, such as the development of microbial colonies and
tumor progression, the local cell growth increases the local pressure, which in turn …
tumor progression, the local cell growth increases the local pressure, which in turn …