The joint analysis of the genome, epigenome, transcriptome, proteome and/or metabolome
from single cells is transforming our understanding of cell biology in health and disease. In …

Spatial omics technologies enable a deeper understanding of cellular organizations and
interactions within a tissue of interest. These assays can identify specific compartments or …

Single-cell transcriptomic approaches have revolutionised the study of complex biological
systems, with the routine measurement of gene expression in thousands of cells enabling …

The ability to explore life kingdoms is largely driven by innovations and breakthroughs in
technology, from the invention of the microscope 350 years ago to the recent emergence of …

In recent years, spatial transcriptomics (ST) technologies have developed rapidly and have
been widely used in constructing spatial tissue atlases and characterizing spatiotemporal …

We present spatial-CITE-seq for high-plex protein and whole transcriptome co-mapping,
which was firstly demonstrated for profiling 189 proteins and transcriptome in multiple …

All multicellular organisms are closely associated with microbes, which have a major impact
on the health of their host. The interactions of microbes among themselves and with the host …

Current streamline of precision medicine uses histomorphological and molecular
information to indicate individual phenotypes and genotypes to achieve optimal outcome of …

Tumor-infiltrating macrophages support critical steps in tumor progression, and their
accumulation in the tumor microenvironment (TME) is associated with adverse outcomes …

Throughout the 20th Century, regulatory peptide discovery advanced from the identification
of gut hormones to the extraction and characterization of hypothalamic hypophysiotropic …