Visible‐light photocatalysis: does it make a difference in organic synthesis?

L Marzo, SK Pagire, O Reiser… - Angewandte Chemie …, 2018 - Wiley Online Library
Visible‐light photocatalysis has evolved over the last decade into a widely used method in
organic synthesis. Photocatalytic variants have been reported for many important …

Modern transition-metal-catalyzed carbon–halogen bond formation

DA Petrone, J Ye, M Lautens - Chemical Reviews, 2016 - ACS Publications
The high utility of halogenated organic compounds has prompted the development of a vast
number of transformations which install the carbon–halogen motif. Traditional routes to …

Use of bromine and bromo-organic compounds in organic synthesis

I Saikia, AJ Borah, P Phukan - Chemical reviews, 2016 - ACS Publications
Bromination is one of the most important transformations in organic synthesis and can be
carried out using bromine and many other bromo compounds. Use of molecular bromine in …

Enzymatic halogenation and dehalogenation reactions: pervasive and mechanistically diverse

V Agarwal, ZD Miles, JM Winter, AS Eustáquio… - Chemical …, 2017 - ACS Publications
Naturally produced halogenated compounds are ubiquitous across all domains of life where
they perform a multitude of biological functions and adopt a diversity of chemical structures …

Expanding the enzyme universe: accessing non‐natural reactions by mechanism‐guided directed evolution

H Renata, ZJ Wang, FH Arnold - … Chemie International Edition, 2015 - Wiley Online Library
High selectivity and exquisite control over the outcome of reactions entice chemists to use
biocatalysts in organic synthesis. However, many useful reactions are not accessible …

Catalytic mechanisms of Fe (II)-and 2-oxoglutarate-dependent oxygenases

S Martinez, RP Hausinger - Journal of Biological Chemistry, 2015 - ASBMB
Mononuclear non-heme Fe (II)-and 2-oxoglutarate (2OG)-dependent oxygenases comprise
a large family of enzymes that utilize an Fe (IV)-oxo intermediate to initiate diverse oxidative …

Photokatalyse mit sichtbarem Licht: Welche Bedeutung hat sie für die organische Synthese?

L Marzo, SK Pagire, O Reiser, B König - Angewandte Chemie, 2018 - Wiley Online Library
Abstract Die Photokatalyse mit sichtbarem Licht hat sich im letzten Jahrzehnt zu einer breit
angewandten Methode in der organischen Synthese entwickelt. Für viele wichtige …

Modular difunctionalization of unactivated alkenes through bio-inspired radical ligand transfer catalysis

KJ Bian, D Nemoto Jr, SC Kao, Y He, Y Li… - Journal of the …, 2022 - ACS Publications
Development of visible light-mediated atom transfer radical addition of haloalkanes onto
unsaturated hydrocarbons has seen rapid growth in recent years. However, due to its radical …

General and modular route to (Halo) alkyl BCP-heteroaryls enabled by α-aminoalkyl radical-mediated halogen-atom transfer

Y Guo, J Zhu, Y Wang, Y Li, H Hu, P Zhang, J Xu… - ACS …, 2023 - ACS Publications
Synthesis of bicyclo [1.1. 1] pentane (BCP) heteroaryls continues to be a part of the most
important tasks in organic synthesis because they are a significant class of bioisosteres with …

Genomes to natural products prediction informatics for secondary metabolomes (PRISM)

MA Skinnider, CA Dejong, PN Rees… - Nucleic acids …, 2015 - academic.oup.com
Microbial natural products are an invaluable source of evolved bioactive small molecules
and pharmaceutical agents. Next-generation and metagenomic sequencing indicates …