Metabolic reprogramming of the intestinal microbiome with functional bile acid changes underlie the development of NAFLD

E Smirnova, MD Muthiah, N Narayan, MS Siddiqui… - Hepatology, 2022 - journals.lww.com
Autoimmune hepatitis (AIH) is a rare disease of unclear etiology characterized by loss of self‐
tolerance that can lead to liver injury, cirrhosis, and acute liver failure. First‐line treatment …

Impact of food additives on the composition and function of gut microbiota: A review

Y Cao, H Liu, N Qin, X Ren, B Zhu, X Xia - Trends in Food Science & …, 2020 - Elsevier
Background Dietary factors substantially influence the community structure and function of
human gut microbiota. Although many dietary components, such as carbohydrates, fats …

Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring

LE Colbert, MB El Alam, R Wang, T Karpinets, D Lo… - Cancer Cell, 2023 - cell.com
Tumor microbiota can produce active metabolites that affect cancer and immune cell
signaling, metabolism, and proliferation. Here, we explore tumor and gut microbiome …

Microbiome and gut dysbiosis

JE Belizário, J Faintuch - Metabolic interaction in infection, 2018 - Springer
The gastrointestinal (GI) tract is the residence of trillions of microorganisms that include
bacteria, archaea, fungi and viruses. The collective genomes of whole microbial …

Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice

F Hildebrand, TLA Nguyen, B Brinkman, RG Yunta… - Genome biology, 2013 - Springer
Background Murine models are a crucial component of gut microbiome research.
Unfortunately, a multitude of genetic backgrounds and experimental setups, together with …

Getting started with microbiome analysis: sample acquisition to bioinformatics

R Kumar, P Eipers, RB Little, M Crowley… - Current protocols in …, 2014 - Wiley Online Library
Historically, in order to study microbes, it was necessary to grow them in the laboratory. It
was clear though that many microbe communities were refractory to study because none of …

Metagenomic analysis using phylogenetic placement—a review of the first decade

L Czech, A Stamatakis, M Dunthorn… - Frontiers in …, 2022 - frontiersin.org
Phylogenetic placement refers to a family of tools and methods to analyze, visualize, and
interpret the tsunami of metagenomic sequencing data generated by high-throughput …

Of microbes and minds: a narrative review on the second brain aging

R Calvani, A Picca, MR Lo Monaco, F Landi… - Frontiers in …, 2018 - frontiersin.org
In recent years, an extensive body of literature focused on the gut–brain axis and the
possible role played by the gut microbiota in modulating brain morphology and function from …

Gut microbiota and old age: Modulating factors and interventions for healthy longevity

V Coman, DC Vodnar - Experimental gerontology, 2020 - Elsevier
Our gut microbiota is a complex and dynamic ecosystem with a paramount role in shaping
our metabolic and immunological functions. Recent research suggests that aging may …

The oral microbiome and oral cancer

L Wang, I Ganly - Clinics in laboratory medicine, 2014 - labmed.theclinics.com
Bacteria have been linked to cancer through several mechanisms such as production of
toxins, chronic inflammation, and carcinogenic metabolites. Several bacteria are thought to …