Background: Cancer accounts for several deaths each year. There are multiple FDA
approved drugs for cancer treatments. Due to the severe side effects and multiple drug …

Breast cancer is the second most leading cause of death among women. Multiple drugs
have been approved by FDA for the treatment of BC. The major drawbacks of existing drugs …

Abstract Background Coronavirus disease-2019 (COVID-19) is an infectious pandemic
caused by SARS-CoV-2. SARS-CoV-2 main protease (M pro) and spike protein are crucial …

Tubulin, an important clinical molecular target, has attracted high attention in drug design
development and cancer treatment. Tubulin inhibitors cause cell cycle arrest in the G 2/M …

Background: Breast Cancer (BC) is the second most common cause of cancer related
deaths in women. Due to severe side effects and multidrug resistance, current therapies like …

A novel quinolinyl pyrrolone and quinolinyl pyridazinone derivatives has been synthesized
and characterized using different spectroscopic and elemental analysis techniques. Most of …

In this study, new Schiff bases and β-lactam derivatives containing morpholine and thio
morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and …

BACKGROUND Quinoline derivatives possess excellent fungicidal activity against rice blast,
but quinoline derivatives have not been thoroughly explored as fungicides. In the process of …

Novel quinoline derivatives carrying nitrones and oxime as nitric oxide donors were
prepared and characterized using different spectroscopic techniques. Nitrones can release …

COVID-19 is an infectious pandemic caused by the SARS-CoV-2 virus. The critical
components of SARS-CoV-2 are the spike protein (S-protein) and the main protease (Mpro) …