Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers

R Hamam, D Hamam, KA Alsaleh, M Kassem… - Cell death & …, 2017 - nature.com
Effective management of breast cancer depends on early diagnosis and proper monitoring
of patients' response to therapy. However, these goals are difficult to achieve because of the …

The ID proteins: master regulators of cancer stem cells and tumour aggressiveness

A Lasorella, R Benezra, A Iavarone - Nature Reviews Cancer, 2014 - nature.com
Inhibitor of DNA binding (ID) proteins are transcriptional regulators that control the timing of
cell fate determination and differentiation in stem and progenitor cells during normal …

[HTML][HTML] CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter

SR Choudhury, Y Cui, K Lubecka, B Stefanska… - Oncotarget, 2016 - ncbi.nlm.nih.gov
DNA hypermethylation at the promoter of tumour-suppressor genes is tightly correlated with
their transcriptional repression and recognized as the hallmark of majority of cancers …

Regulation of breast cancer metastasis signaling by miRNAs

BJ Petri, CM Klinge - Cancer and metastasis reviews, 2020 - Springer
Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Control of metastatic progression by microRNA regulatory networks

N Pencheva, SF Tavazoie - Nature cell biology, 2013 - nature.com
Aberrant microRNA (miRNA) expression is a defining feature of human malignancy. Specific
miRNAs have been identified as promoters or suppressors of metastatic progression …

MicroRNAs in breast cancer: oncogene and tumor suppressors with clinical potential

W Wang, Y Luo - Journal of Zhejiang University-SCIENCE B, 2015 - Springer
MicroRNAs (miRs) are small single-stranded RNA molecules, which function as key
negative regulators of post-transcriptional modulation in almost all biological processes …

MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells

C Wang, X Zheng, C Shen, Y Shi - Journal of experimental & clinical …, 2012 - Springer
Background This study was performed to investigate the effect of microRNA-203 (miR-203)
on cell proliferation and migration in triple-negative breast cancer (TNBC). Methods Real …

Identification of a six‐microRNA signature as a potential diagnostic biomarker in breast cancer tissues

M Mahmoudian, E Razmara… - Journal of clinical …, 2021 - Wiley Online Library
Background Breast cancer (BC) is by far the most common malignancy among women.
Epigenetic modulators, microRNAs in particular, may set stages for BC development and its …

LncRNA SNHG7 promotes pancreatic cancer proliferation through ID4 by sponging miR-342-3p

D Cheng, J Fan, Y Ma, Y Zhou, K Qin, M Shi, J Yang - Cell & bioscience, 2019 - Springer
Background Small nucleolar RNA host gene 7 (SNHG7) is a novel identified oncogenic
gene in tumorigenesis. However, the role that SNHG7 plays in pancreatic cancer (PC) …

Circulating miRNAs in breast cancer diagnosis and prognosis

B Cardinali, R Tasso, P Piccioli, MC Ciferri, R Quarto… - Cancers, 2022 - mdpi.com
Simple Summary In the era of precision medicine, new tools for better management of breast
cancer patients are still needed. From this perspective, circulating microRNA (miRNA), a …