Environmental exposures and mechanisms in allergy and asthma development

LB Murrison, EB Brandt, JB Myers… - The Journal of clinical …, 2019 - Am Soc Clin Investig
Environmental exposures interplay with human host factors to promote the development and
progression of allergic diseases. The worldwide prevalence of allergic disease is rising as a …

Neuroimmune interactions in peripheral organs

RGJ Klein Wolterink, GS Wu, IM Chiu… - Annual review of …, 2022 - annualreviews.org
Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …

[HTML][HTML] Substance P release by sensory neurons triggers dendritic cell migration and initiates the type-2 immune response to allergens

C Perner, CH Flayer, X Zhu, PA Aderhold, ZNA Dewan… - Immunity, 2020 - cell.com
Dendritic cells (DCs) of the cDC2 lineage initiate allergic immunity and in the dermis are
marked by their expression of CD301b. CD301b+ dermal DCs respond to allergens …

Edible insects as a food source: a review

C Tang, D Yang, H Liao, H Sun, C Liu, L Wei… - … , Processing and Nutrition, 2019 - Springer
The practice of eating insects has been documented for a long time. With obvious economic
and environmental advantages, edible insects are in the spotlight recently due to their …

Glycosidase-targeting small molecules for biological and therapeutic applications

Y Kim, H Li, J Choi, J Boo, H Jo, JY Hyun… - Chemical Society …, 2023 - pubs.rsc.org
Glycosidases are ubiquitous enzymes that catalyze the hydrolysis of glycosidic linkages in
oligosaccharides and glycoconjugates. These enzymes play a vital role in a wide variety of …

Chitinases as key virulence factors in microbial pathogens: understanding their role and potential as therapeutic targets

GJ Jeong, F Khan, N Tabassum, YM Kim - International Journal of …, 2023 - Elsevier
Chitinases are crucial for the survival of bacterial and fungal pathogens both during host
infection and outside the host in the environment. Chitinases facilitate adhesion onto host …

Novel mechanistic insights underlying fungal allergic inflammation

Y Zheng, EV Dang - PLoS Pathogens, 2023 - journals.plos.org
The worldwide prevalence of asthma and allergic disorders (allergic rhinitis, atopic
dermatitis, food allergy) has been steadily rising in recent decades. It is now estimated that …

Screening of bioactive compounds in truffles and evaluation of pressurized liquid extractions (PLE) to obtain fractions with biological activities

E Tejedor-Calvo, D Morales, P Marco… - Food Research …, 2020 - Elsevier
Truffles, besides the appreciated aromatic compounds, contain other molecules with
interesting bioactive properties. A screening of fungal sterols and β-glucans within different …

The airway epithelium in asthma

LR Bonser, DJ Erle - Advances in immunology, 2019 - Elsevier
Asthma is a genetically and phenotypically complex disease that has a major impact on
global health. Signs and symptoms of asthma are caused by the obstruction of airflow …

Inflammatory checkpoints in amyotrophic lateral sclerosis: From biomarkers to therapeutic targets

Z Jiang, Z Wang, X Wei, XF Yu - Frontiers in Immunology, 2022 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by
progressive motor neuron damage. Due to the complexity of the ALS, so far the etiology and …