Applying the latest advances in genomics and phenomics for trait discovery in polyploid wheat

P Borrill, SA Harrington, C Uauy - The Plant Journal, 2019 - Wiley Online Library
Improving traits in wheat has historically been challenging due to its large and polyploid
genome, limited genetic diversity and in‐field phenotyping constraints. However, within …

Genomics as the key to unlocking the polyploid potential of wheat

P Borrill, N Adamski, C Uauy - New Phytologist, 2015 - Wiley Online Library
Polyploidy has played a central role in plant genome evolution and in the formation of new
species such as tetraploid pasta wheat and hexaploid bread wheat. Until recently, the high …

An unusual tandem kinase fusion protein confers leaf rust resistance in wheat

Y Wang, M Abrouk, S Gourdoupis, DH Koo… - Nature …, 2023 - nature.com
The introgression of chromosome segments from wild relatives is an established strategy to
enrich crop germplasm with disease-resistance genes. Here we use mutagenesis and …

Dissection of a rapidly evolving wheat resistance gene cluster by long-read genome sequencing accelerated the cloning of Pm69

Y Li, ZZ Wei, H Sela, L Govta, V Klymiuk… - Plant …, 2024 - cell.com
Gene cloning in repeat-rich polyploid genomes remains challenging. Here, we describe a
strategy for overcoming major bottlenecks in cloning of the powdery mildew resistance gene …

Wheat Pm4 resistance to powdery mildew is controlled by alternative splice variants encoding chimeric proteins

J Sánchez-Martín, V Widrig, G Herren, T Wicker… - Nature Plants, 2021 - nature.com
Crop breeding for resistance to pathogens largely relies on genes encoding receptors that
confer race-specific immunity. Here, we report the identification of the wheat Pm4 race …

Rapid gene isolation in barley and wheat by mutant chromosome sequencing

J Sánchez-Martín, B Steuernagel, S Ghosh, G Herren… - Genome biology, 2016 - Springer
Identification of causal mutations in barley and wheat is hampered by their large genomes
and suppressed recombination. To overcome these obstacles, we have developed …

The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase

G Yu, O Matny, S Gourdoupis, N Rayapuram… - Nature Genetics, 2023 - nature.com
To safeguard bread wheat against pests and diseases, breeders have introduced over 200
resistance genes into its genome, thus nearly doubling the number of designated resistance …

Aegilops sharonensis genome-assisted identification of stem rust resistance gene Sr62

G Yu, O Matny, N Champouret, B Steuernagel… - Nature …, 2022 - nature.com
The wild relatives and progenitors of wheat have been widely used as sources of disease
resistance (R) genes. Molecular identification and characterization of these R genes …

A membrane-bound ankyrin repeat protein confers race-specific leaf rust disease resistance in wheat

MC Kolodziej, J Singla, J Sánchez-Martín… - Nature …, 2021 - nature.com
Plasma membrane-associated and intracellular proteins and protein complexes play a
pivotal role in pathogen recognition and disease resistance signaling in plants and animals …

Rapid cloning of genes in hexaploid wheat using cultivar-specific long-range chromosome assembly

AK Thind, T Wicker, H Šimková, D Fossati… - Nature …, 2017 - nature.com
Cereal crops such as wheat and maize have large repeat-rich genomes that make cloning of
individual genes challenging. Moreover, gene order and gene sequences often differ …