Prenatal opioid exposure: neurodevelopmental consequences and future research priorities

E Conradt, T Flannery, JL Aschner, RD Annett… - …, 2019 - publications.aap.org
Neonatal opioid withdrawal syndrome (NOWS) has risen in prevalence from 1.2 per 1000
births in 2000 to 5.8 per 1000 births in 2012. Symptoms in neonates may include high …

Neurodevelopmental outcomes of children born to opioid-dependent mothers: a systematic review and meta-analysis

SJ Lee, S Bora, NC Austin, A Westerman… - Academic pediatrics, 2020 - Elsevier
Background Children born to opioid-dependent mothers are at risk of adverse
neurodevelopment. The magnitude of this risk remains inconclusive. Objective To conduct a …

Prenatal risk factors and perinatal and postnatal outcomes associated with maternal opioid exposure in an urban, low-income, multiethnic US population

RE Azuine, Y Ji, HY Chang, Y Kim, H Ji… - JAMA network …, 2019 - jamanetwork.com
Importance The opioid epidemic increasingly affects pregnant women and developing
fetuses, resulting in high rates of neonatal abstinence syndrome. However, longitudinal …

Impact of mother–infant interaction on development during the first year of life: A systematic review

NACF Rocha, FP dos Santos Silva… - Journal of Child …, 2020 - journals.sagepub.com
The objectives of this project were to systematically review the impact of mother–infant
interaction on the development of infants 12 months or younger and determine factors that …

The COVID-19 pandemic and early child cognitive development: a comparison of development in children born during the pandemic and historical references

SCL Deoni, J Beauchemin, A Volpe, V D'Sa… - MedRxiv, 2021 - medrxiv.org
Objective To characterize cognitive function in young children under 3 years of age over the
past decade, and test whether children exhibit different cognitive development profiles …

Modeling prenatal opioid exposure in animals: current findings and future directions

EM Byrnes, FM Vassoler - Frontiers in neuroendocrinology, 2018 - Elsevier
The past decade has seen a drastic rise in the number of infants exposed to opioids in utero.
It is unclear what lasting effect this exposure may have on these children. Animal models of …

Mothering, substance use disorders and intergenerational trauma transmission: an attachment-based perspective

F Meulewaeter, SSW De Pauw… - Frontiers in …, 2019 - frontiersin.org
Background: A growing body of research underlines that interpersonal trauma in childhood
leads to heightened susceptibility for substance use disorders (SUDs) in later life. Little …

Neurobehavior of newborn infants exposed prenatally to methadone and identification of a neurobehavioral profile linked to poorer neurodevelopmental outcomes at …

TA Wouldes, LJ Woodward - PLoS One, 2020 - journals.plos.org
The abuse of prescription opioids and heroin by women of childbearing age over the past
decade has resulted in a five-fold increase in the number of infants born opioid-dependent …

Prenatal exposure to opioids and neurodevelopment in infancy and childhood: a systematic review

AA Balalian, R Graeve, M Richter, A Fink… - Frontiers in …, 2023 - frontiersin.org
Aim This systematic review aims to estimate the relationship between prenatal exposure to
opioids and neurodevelopmental outcomes and examines potential sources of …

Association between prenatal opioid exposure, neonatal opioid withdrawal syndrome, and neurodevelopmental and behavioral outcomes at 5–8 months of age

LN Bakhireva, BD Holbrook, S Shrestha, Y Leyva… - Early human …, 2019 - Elsevier
Background While use of prescription opioids and medication assisted therapy (MAT) for
opioid use disorder in pregnancy, as well as the incidence of neonatal opioid withdrawal …