Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion

SJ Dando, A Mackay-Sim, R Norton… - Clinical microbiology …, 2014 - Am Soc Microbiol
The brain is well protected against microbial invasion by cellular barriers, such as the blood-
brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells …

C ell therapy for spinal cord injury with olfactory ensheathing glia cells (OEC s)

RM Gómez, MY Sánchez, M Portela‐Lomba, K Ghotme… - Glia, 2018 - Wiley Online Library
The prospects of achieving regeneration in the central nervous system (CNS) have
changed, as most recent findings indicate that several species, including humans, can …

[HTML][HTML] Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer's disease risk

A Chacko, A Delbaz, H Walkden, S Basu… - Scientific reports, 2022 - nature.com
Chlamydia pneumoniae is a respiratory tract pathogen but can also infect the central
nervous system (CNS). Recently, the link between C. pneumoniae CNS infection and late …

[HTML][HTML] Generation of three-dimensional multiple spheroid model of olfactory ensheathing cells using floating liquid marbles

RK Vadivelu, CH Ooi, RQ Yao, J Tello Velasquez… - Scientific reports, 2015 - nature.com
We describe a novel protocol for three-dimensional culturing of olfactory ensheathing cells
(OECs), which can be used to understand how OECs interact with other cells in three …

Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage …

DA Hume - Journal of leukocyte biology, 2011 - academic.oup.com
Myeloid lineage cells contribute to innate and acquired immunity, homeostasis, wound
repair, and inflammation. There is considerable interest in manipulation of their function in …

Understanding the neural repair-promoting properties of olfactory ensheathing cells

KCD Roet, J Verhaagen - Experimental neurology, 2014 - Elsevier
Olfactory ensheathing glial cells (OECs) are a specialized type of glia that form a
continuously aligned cellular pathway that actively supports unprecedented regeneration of …

Olfactory ensheathing cells: biology in neural development and regeneration

Z Su, C He - Progress in neurobiology, 2010 - Elsevier
Olfactory ensheathing cells (OECs) constitute a unique population of glia that accompany
and ensheath the primary olfactory axons. They are thought to be critical for spontaneous …

Survival and integration of transplanted olfactory ensheathing cells are crucial for spinal cord injury repair: insights from the last 10 years of animal model studies

R Reshamwala, M Shah, J St John… - Cell …, 2019 - journals.sagepub.com
Olfactory ensheathing cells (OECs), the glial cells of the primary olfactory nervous system,
support the natural regeneration of the olfactory nerve that occurs throughout life. OECs thus …

[HTML][HTML] Antioxidant and anti-senescence effect of metformin on mouse olfactory ensheathing cells (mOECs) may be associated with increased brain-derived …

A Śmieszek, Z Stręk, K Kornicka, J Grzesiak… - International journal of …, 2017 - mdpi.com
Metformin, the popular anti-diabetic drug was shown to exert multiple biological effects. The
most recent metformin gained attention as an agent that mobilizes endogenous progenitor …

Olfactory ensheathing cells are the main phagocytic cells that remove axon debris during early development of the olfactory system

L Nazareth, KE Lineburg, MI Chuah… - Journal of …, 2015 - Wiley Online Library
During development of the primary olfactory system, axon targeting is inaccurate and axons
inappropriately project within the target layer or overproject into the deeper layers of the …