Candida Infections of the Genitourinary Tract
JM Achkar, BC Fries - Clinical microbiology reviews, 2010 - Am Soc Microbiol
All humans are colonized with Candida species, mostly Candida albicans, yet some develop
diseases due to Candida, among which genitourinary manifestations are extremely …
diseases due to Candida, among which genitourinary manifestations are extremely …
Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
A fungal immunotherapeutic vaccine (NDV-3A) for treatment of recurrent vulvovaginal candidiasis—a phase 2 randomized, double-blind, placebo-controlled trial
JE Edwards Jr, MM Schwartz… - Clinical Infectious …, 2018 - academic.oup.com
Background Recurrent vulvovaginal candidiasis (RVVC) is a problematic form of mucosal
Candida infection, characterized by repeated episodes per year. Candida albicans is the …
Candida infection, characterized by repeated episodes per year. Candida albicans is the …
[HTML][HTML] An insight into the antifungal pipeline: selected new molecules and beyond
L Ostrosky-Zeichner, A Casadevall… - Nature reviews Drug …, 2010 - nature.com
Invasive fungal infections are increasing in incidence and are associated with substantial
mortality. Improved diagnostics and the availability of new antifungals have revolutionized …
mortality. Improved diagnostics and the availability of new antifungals have revolutionized …
Candida albicans Cell Wall Proteins
WLJ Chaffin - Microbiology and molecular biology reviews, 2008 - Am Soc Microbiol
The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …
providing a physical contact interface with the environment. The major components of the …
[HTML][HTML] Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells
QT Phan, CL Myers, Y Fu, DC Sheppard… - PLoS …, 2007 - journals.plos.org
Candida albicans is the most common cause of hematogenously disseminated and
oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of …
oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of …
A Pseudomonas aeruginosa quorum‐sensing molecule influences Candida albicans morphology
DA Hogan, Å Vik, R Kolter - Molecular microbiology, 2004 - Wiley Online Library
Candida albicans is an opportunistic pathogen that is commonly found as a member of the
human microflora. The ability of C. albicans to alter its cellular morphology has been …
human microflora. The ability of C. albicans to alter its cellular morphology has been …
Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …
gastrointestinal flora of most healthy humans. However, under certain environmental …
[HTML][HTML] Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo
The fungal pathogen Candida albicans is frequently associated with catheter-based
infections because of its ability to form resilient biofilms. Prior studies have shown that the …
infections because of its ability to form resilient biofilms. Prior studies have shown that the …
[HTML][HTML] CotH3 mediates fungal invasion of host cells during mucormycosis
T Gebremariam, M Liu, G Luo, V Bruno… - The Journal of …, 2014 - Am Soc Clin Investig
Angioinvasion is a hallmark of mucormycosis. Previously, we identified endothelial cell
glucose-regulated protein 78 (GRP78) as a receptor for Mucorales that mediates host cell …
glucose-regulated protein 78 (GRP78) as a receptor for Mucorales that mediates host cell …