Cancer researchers have traditionally used the mouse and the rat as staple model
organisms. These animals are very short-lived, reproduce rapidly and are highly prone to …

The ongoing West African Ebola epidemic highlights a recurring trend in the zoonotic
emergence of virulent pathogens likely to come from bat reservoirs that has caused …

Lifespan varies within and across species, but the general principles of its control remain
unclear. Here, we conducted multi-tissue RNA-seq analyses across 41 mammalian species …

DNA repair has been hypothesized to be a longevity determinant, but the evidence for it is
based largely on accelerated aging phenotypes of DNA repair mutants. Here, using a panel …

Importance Evolutionary medicine may provide insights into human physiology and
pathophysiology, including tumor biology. Objective To identify mechanisms for cancer …

The ageing of populations worldwide is leading to an unprecedented increase in cancer
cases and fatalities. Understanding the links between cancer and ageing is therefore more …

Longevity is a major characteristic of animals that has long fascinated scientists. In this work,
we present a comprehensive database of animal longevity records and related life‐history …

Males and females often age at different rates resulting in longevity 'gender gaps', where
one sex outlives the other. Why the sexes have different lifespans is an age‐old question …

Hyaluronic acid (HA) is a linear polysaccharide and crucial component of the extracellular
matrix (ECM), maintaining tissue hydration and tension. Moreover, HA contributes to …

The naked mole-rat is the longest living rodent with a maximum lifespan exceeding 28
years. In addition to its longevity, naked mole-rats have an extraordinary resistance to …