Xenotransplantation may be a solution to overcome the shortage of organs for the treatment
of patients with organ failure, but it may be associated with the transmission of porcine …

An urgent and steadily increasing need exists worldwide for a greater supply of donor
thoracic organs. Xenotransplantation offers the possibility of an unlimited supply of hearts …

OBJECTIVE: We compared 3 different decellularization protocols in porcine heart valves for
efficiency of complete cell removal and potential for recellularization. METHODS: Porcine …

Pig organs may offer a solution to the shortage of human donor organs for transplantation,
but concerns remain about possible cross-species transmission of porcine endogenous …

Background—Tissue engineering using in vitro–cultivated autologous vascular wall cells is
a new approach to biological heart valve replacement. In the present study, we analyzed a …

To determine its efficacy in stimulating the regeneration of a rotator cuff tendon, an implant of
10-ply porcine small intestinal submucosa was used to replace a completely resected …

Background: The pig is an economically important food source, amounting to approximately
40% of all meat consumed worldwide. Pigs also serve as an important model organism …

In view of the concern over potential infection hazards in the use of porcine tissues and
organs for xenotransplantation to humans, we investigated the diversity of porcine …

Background: The presence of multiple copies of porcine endogenous retrovirus (PERV)
within the pig genome, and the demonstration that replication competent PERV, that infect …

Background: Xenotransplantation using porcine cells, tissues or organs may be associated
with the transmission of porcine endogenous retroviruses (PERVs). More than 50 viral …