New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy

S Victor, E Rocha-Ferreira, A Rahim, H Hagberg… - European journal of …, 2022 - Springer
Around 0.75 million babies worldwide suffer from moderate or severe hypoxic-ischemic
encephalopathy (HIE) each year resulting in around 400,000 babies with …

Advances in therapies to treat neonatal hypoxic-ischemic encephalopathy

AK Ranjan, A Gulati - Journal of clinical medicine, 2023 - mdpi.com
Neonatal hypoxic-ischemic encephalopathy (HIE) is a condition that results in brain damage
in newborns due to insufficient blood and oxygen supply during or after birth. HIE is a major …

Hypoxic-ischemic encephalopathy: pathogenesis and promising therapies

M Yang, K Wang, B Liu, Y Shen, G Liu - Molecular neurobiology, 2024 - Springer
Hypoxic-ischemic encephalopathy (HIE) is a brain lesion caused by inadequate blood
supply and oxygen deprivation, often occurring in neonates. It has emerged as a grave …

Human umbilical cord blood mononuclear cells transplantation for perinatal brain injury

Y Xi, G Yue, S Gao, R Ju, Y Wang - Stem Cell Research & Therapy, 2022 - Springer
Perinatal brain injury is a leading cause of death and disability in children. Hypoxic-ischemic
encephalopathy in full term infants, and white matter injury in premature infants are most …

A pilot phase i trial of allogeneic umbilical cord tissue-derived mesenchymal stromal cells in neonates with hypoxic-ischemic encephalopathy

CM Cotten, K Fisher, W Malcolm… - Stem Cells …, 2023 - academic.oup.com
Hypoxic ischemic encephalopathy (HIE) in neonates causes increased mortality and long-
term morbidity in surviving babies. Hypothermia (HT) has improved outcomes, however …

[HTML][HTML] A narrative review on treatment strategies for neonatal hypoxic ischemic encephalopathy

JM Korf, LD McCullough, V Caretti - Translational Pediatrics, 2023 - ncbi.nlm.nih.gov
Methods We included full articles and book chapters published in English on PubMed with
references to “hypoxic ischemic encephalopathy”,“birth asphyxia”,“therapeutic hypothermia” …

Neonatal asphyxia as an inflammatory disease: reactive oxygen species and cytokines

K Okazaki, S Nakamura, K Koyano, Y Konishi… - Frontiers in …, 2023 - frontiersin.org
Neonatologists resuscitate asphyxiated neonates by every available means, including
positive ventilation, oxygen therapy, and drugs. Asphyxiated neonates sometimes present …

The potential of mesenchymal stromal cell as therapy in neonatal diseases

LL Liau, ME Al-Masawa, B Koh, QH Looi, JB Foo… - Frontiers in …, 2020 - frontiersin.org
Mesenchymal stromal cells (MSCs) can be derived from various tissue sources, such as the
bone marrow (BMSCs), adipose tissue (ADSCs), umbilical cord (UC-MSCs) and umbilical …

Mesenchymal stem cell therapy in perinatal arterial ischemic stroke: systematic review of preclinical studies

V Lehnerer, A Roidl, O Romantsik, R Guzman… - Pediatric …, 2024 - nature.com
Background Perinatal arterial ischemic stroke (PAIS) is a neurologic disorder leading to long-
term complications. Mesenchymal stem cells (MSCs) have emerged as a novel therapeutic …

Stem cell therapy for diabetic foot ulcers: Theory and practice

DL Nalisa, M Moneruzzaman… - Journal of Diabetes …, 2022 - Wiley Online Library
Diabetic foot ulcers are associated with increases in limb amputation, morbidity, and
mortality. Recently, a stem cell application is emerging as promising adjuvant therapy. We …