Background Unraveling the mechanisms that regulate gene expression is a major challenge
in biology. An important task in this challenge is to identify regulatory elements, especially …

The DNA motif discovery is a primary step in many systems for studying gene function. Motif
discovery plays a vital role in identification of Transcription Factor Binding Sites (TFBSs) that …

Background Accurate prediction of DNA motifs that are targets of RNA polymerases, sigma
factors and transcription factors (TFs) in prokaryotes is a difficult mission mainly due to as yet …

We present CisFinder software, which generates a comprehensive list of motifs enriched in a
set of DNA sequences and describes them with position frequency matrices (PFMs). A new …

Genome-wide analyses of protein binding sites generate large amounts of data; a ChIP
dataset might contain 10,000 sites. Unbiased motif discovery in such datasets is not …

Computational DNA motif discovery is important because it allows for speedy and cost
effective analysis of sequences enriched with DNA motifs, performs large scale comparative …

Motivation: Identification of transcription factor binding sites (TFBSs) plays an important role
in deciphering the mechanisms of gene regulation. Recently, GAME, a Genetic Algorithm …

We propose an improved solution to the three-stage DNA motif prediction approach. The
three-stage approach uses only a subset of input sequences for initial motif prediction, and …

Possessing great potential power for gathering and managing data in chemistry, biology,
and other sciences, Artificial Intelligence (AI) methods are prompting increased exploration …

Proteins are molecules that form the mass of living beings. These proteins exist in
dissociated forms like amino-acids and carry out various biological functions, in fact, almost …