Immune activation, inflammation, and non-AIDS co-morbidities in HIV-infected patients under long-term ART
Despite effective antiretroviral therapy (ART), people living with HIV (PLWH) still present
persistent chronic immune activation and inflammation. This condition is the result of several …
persistent chronic immune activation and inflammation. This condition is the result of several …
Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases
C Sturgeon, A Fasano - Tissue barriers, 2016 - Taylor & Francis
Beside digesting nutrients and absorbing solutes and electrolytes, the intestinal epithelium
with its barrier function is in charge of a tightly controlled antigen trafficking from the …
with its barrier function is in charge of a tightly controlled antigen trafficking from the …
[HTML][HTML] Age-associated microbial dysbiosis promotes intestinal permeability, systemic inflammation, and macrophage dysfunction
N Thevaranjan, A Puchta, C Schulz, A Naidoo… - Cell host & …, 2017 - cell.com
Levels of inflammatory mediators in circulation are known to increase with age, but the
underlying cause of this age-associated inflammation is debated. We find that, when …
underlying cause of this age-associated inflammation is debated. We find that, when …
The end of AIDS: HIV infection as a chronic disease
The success of antiretroviral therapy has led some people to now ask whether the end of
AIDS is possible. For patients who are motivated to take therapy and who have access to …
AIDS is possible. For patients who are motivated to take therapy and who have access to …
[HTML][HTML] National Lipid Association recommendations for patient-centered management of dyslipidemia: part 2
TA Jacobson, KC Maki, CE Orringer, PH Jones… - Journal of clinical …, 2015 - Elsevier
Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …
a consensus set of recommendations for the patient-centered management of dyslipidemia …
Cross-sectional Comparison of the Prevalence of Age-Associated Comorbidities and Their Risk Factors Between HIV-Infected and Uninfected Individuals: The AGEh …
J Schouten, FW Wit, IG Stolte… - Clinical Infectious …, 2014 - academic.oup.com
Age-associated comorbidities (cardiovascular and renal disease) were more prevalent
among HIV-positive compared with HIV-uninfected patients. Comorbidity was associated …
among HIV-positive compared with HIV-uninfected patients. Comorbidity was associated …
The HIV reservoir in monocytes and macrophages
ME Wong, A Jaworowski, AC Hearps - Frontiers in immunology, 2019 - frontiersin.org
In people living with HIV (PLWH) who are failing or unable to access combination
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …
Systemic effects of inflammation on health during chronic HIV infection
Combination antiretroviral therapy for HIV infection improves immune function and
eliminates the risk of AIDS-related complications but does not restore full health. HIV …
eliminates the risk of AIDS-related complications but does not restore full health. HIV …
Altered virome and bacterial microbiome in human immunodeficiency virus-associated acquired immunodeficiency syndrome
Human immunodeficiency virus (HIV) infection is associated with increased intestinal
translocation of microbial products and enteropathy as well as alterations in gut bacterial …
translocation of microbial products and enteropathy as well as alterations in gut bacterial …
Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy
H Imamichi, RL Dewar… - Proceedings of the …, 2016 - National Acad Sciences
Despite years of plasma HIV-RNA levels< 40 copies per milliliter during combination
antiretroviral therapy (cART), the majority of HIV-infected patients exhibit persistent …
antiretroviral therapy (cART), the majority of HIV-infected patients exhibit persistent …