The oxidative conversion of alicyclic ketones into lactones with permonosulfuric acid was
discovered by Baeyer and Villiger in 1899, and in their honor the general process by which …

A Perspective of our work in the development of innovative synthetic methods within the
discipline of Process Research and Development is presented. Through an overview of …

Tetrahydrofuran, tetrahydropyran, and spiroketal units are the main structural features of
polyether antibiotics. This review deals with the stereocontrolled methods by which these …

A convergent asymmetric synthesis of the calcium ionophore ionomycin has been achieved
through a route that is outlined below. The four illustrated subunits, which comprise the C …

This collection of essays will stimulate the use of ionophores in different research areas. It
includes information on potential breakthroughs in the halogenated derivatives of lasalocid …

The development of the structurally complex MDM2/p53 inhibitor AM-8553 was impeded by
the low yield of the initial synthesis. A second generation synthesis is described that features …

Selenium and its compounds are by no means new in organic chemistry. For many years,
organoselenium chemistry was regarded as quite specialized and was consequently largely …

Pyrrole was discovered in the coal tar by Friedlieb Ferdinand Runge (1794–1867) in May
1834. Only 24 years later—in 1858—it was obtained in a pure state by Thomas Anderson …

Macrolide, ansamycin, and polyether antibiotics belong to the rapidly expanding class of
natural products. Their biological activities and considerable commercial importance …

Tetrahedron Letters,Vol.28,No.lO,pp 1063-1066,1987 0040-4039/87 $3.00 + .OO Printed in Great
Britain Pergamon Journals Ltd. Page 1 Tetrahedron Letters,Vol.28,No.lO,pp 1063-1066,1987 …