Biocompatible, attuned, and congruent stimuli-responsive polymers of synthetic and plants
and animals-based origins are essential raw materials for constructing bio-matching …

The prevalence of ear disorders has spurred efforts to develop drug delivery systems to treat
these conditions. Here, recent advances in drug delivery systems that access the ear …

Brain-derived neurotrophic factor (BDNF) has a crucial function in the central nervous
system and in sensory structures including olfactory and auditory systems. Many studies …

Over the last several decades, both the academic and therapeutic fields have seen
significant progress in the delivery of drugs to the inner ear due to recent delivery methods …

Neurotrophin-3 growth factor can improve cochlear neuron survival, and localized delivery
of this protein to the round window membrane in the middle ear may be able to reverse …

Despite significant advances in the development of therapeutics for hearing loss, drug
delivery to the middle and inner ear remains a challenge. As conventional oral or …

There is growing need for new drug delivery systems for intracochlear application of drugs to
effectively treat inner ear disorders. In this study, we describe the development and …

Aging is considered a contributing factor to many diseases such as cardiovascular disease,
Alzheimer's disease, and hearing loss. Age-related hearing loss, also termed presbycusis, is …

Sensorineural hearing loss (SNHL) affects the inner ear compartment and can be caused by
different factors. Usually, the lack, death, or malfunction of sensory cells deputed to …

The treatment of inner ear disorders always remains a challenge for researchers. The
presence of various physiological barriers, primarily the blood–labyrinth barrier (BLB), limits …