The presence of a mucus layer that covers the surface of a variety of organs has been
capitalized to develop mucoadhesive dosage forms that remain in the administration site for …

The last decade has witnessed enormous research focused on cationic polymers. Cationic
polymers are the subject of intense research as non-viral gene delivery systems, due to their …

Chitosan (CS) is a natural biopolymer used frequently in drug delivery because of its
biodegradability and biocompatibility. Several derivatives of CS have also been synthesized …

Thiolated polymers or designated thiomers are obtained by immobilization of sulhydryl
bearing ligands on the polymeric backbone of well-established polymers such as poly …

Due to thiolation of poly‐and oligosaccharides numerous favorable properties for tissue
engineering and wound healing can be introduced. Poly‐and oligosaccharides can be …

Thiolation of polymers is one of the most appropriate approaches to impart higher
mechanical strength and mucoadhesion. Thiol modification of gum karaya and gum acacia …

The success of mucoadhesive drug delivery systems relies on the type of polymer used,
which becomes adhesive naturally upon hydration. Intended polymers should be able to …

A new mucoadhesive polymer was synthesized by conjugating chitosan to poly (ethylene
glycol) diacrylate (PEGDA) via the Michael type reaction. The product was characterized …

Present study aims at synthesis and characterization of thiolated gum karaya by reacting
karaya gum with 80% thioglycolic acid resulting in esterification and immobilization of thiol …

The purpose of this study was to synthesize and characterize a novel thiolated glycogen, so-
named S-preactivated thiolated glycogen, as a mucosal drug delivery systems and the …