A systematic review on the critical size defect model

A Vajgel, N Mardas, BC Farias, A Petrie… - Clinical oral implants …, 2014 - Wiley Online Library
Objectives To systematically review the literature data regarding the critical size defect
(CSD) in adult rat calvaria and to determine which defect dimensions could be considered …

Can platelet-rich plasma (PRP) improve bone healing? A comparison between the theory and experimental outcomes

A Malhotra, MH Pelletier, Y Yu, WR Walsh - Archives of orthopaedic and …, 2013 - Springer
The increased concentration of platelets within platelet-rich plasma (PRP) provides a vehicle
to deliver supra-physiologic concentrations of growth factors to an injury site, possibly …

Bridging the gap: bone marrow aspiration concentrate reduces autologous bone grafting in osseous defects

M Jäger, M Herten, U Fochtmann… - Journal of …, 2011 - Wiley Online Library
Although autologous bone grafting represents an effective tool to induce osteogenic
regeneration in local bone defects or pseudarthroses, it is associated with significant donor …

Effects of platelet-rich fibrin produced by three centrifugation protocols on bone neoformation in defects created in rat calvaria

DS Ferreira Sávio, LMP Silva, GGD Reis, RJ Denardi… - Platelets, 2023 - Taylor & Francis
This study evaluated the potential of Leukocyte-platelet-rich fibrin (L-PRF; fixed angle
centrifugation protocol), Advanced-platelet-rich fibrin (A-PRF; low-speed fixed angle …

Effects of local platelet-rich plasma injection on the rate of orthodontic tooth movement in a rat model: a histomorphometric study

A Güleç, BÇ Bakkalbaşı, A Cumbul, Ü Uslu… - American Journal of …, 2017 - Elsevier
Introduction The aims of this study were to determine the effects of different concentrations of
platelet-rich plasma (PRP) on alveolar bone density and orthodontic tooth movement …

New and emerging strategies in platelet‐rich plasma application in musculoskeletal regenerative procedures: General overview on still open questions and outlook

F Salamanna, F Veronesi, M Maglio… - BioMed Research …, 2015 - Wiley Online Library
Despite its pervasive use, the clinical efficacy of platelet‐rich plasma (PRP) therapy and the
different mechanisms of action have yet to be established. This overview of the literature is …

Proliferation and differentiation of human tenocytes in response to platelet rich plasma: an in vitro and in vivo study

X Wang, Y Qiu, J Triffitt, A Carr, Z Xia… - Journal of …, 2012 - Wiley Online Library
Platelet rich plasma (PRP) is the autologous plasma fraction with a platelet‐rich cellular
component which is enriched with a number of growth factors. Due to its availability and low …

Association of hyaluronic acid with a collagen scaffold may improve bone healing in critical‐size bone defects

B de Brito Bezerra, MA Mendes Brazão… - Clinical oral implants …, 2012 - Wiley Online Library
Objectives: To evaluate the effects of a 1% hyaluronic acid (HA) gel in combination with an
absorbable collagen sponge (ACS) in the healing of critical‐size calvaria defects in rats …

Comparison of the effects of platelet concentrates produced by high and low-speed centrifugation protocols on the healing of critical-size defects in rat calvaria: A …

LMP da Silva, DSF Sávio, FC de Ávila, RM Vicente… - Platelets, 2022 - Taylor & Francis
The current study evaluated the healing of critical-size defects (CSD) created in rat calvaria
treated with platelet concentrates produced by high-speed (Leukocyte-and Platelet-Rich …

Effects of platelet‐rich plasma and bone marrow mesenchymal stem cells on meniscal repair in the white‐white zone of the meniscus

W Xiao, Y Yang, W Xie, M He, D Liu, Z Cai… - Orthopaedic …, 2021 - Wiley Online Library
Objective To investigate the role of autologous platelet‐rich plasma (PRP) on the repair of
meniscal white‐white zone injury through promoting the proliferation of canine bone marrow …