Smoking is a major risk factor for a variety of diseases, including cancer and immune-
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …

Chromatin is a macromolecular complex predominantly comprising DNA, histone proteins
and RNA. The methylation of chromatin components is highly conserved as it helps …

Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-
malignant diseases. This is consistent with numerous findings about differentiation …

Cancer is a major global health burden and poor survival rates can be attributed to lack of
early diagnosis and limited access to timely and standard treatments. Significant progress …

Human diseases such as cancer can be caused by aberrant epigenetic regulation.
Polyphenols play a major role in mammalian epigenome regulation through mechanisms …

Pyroptosis is a newly discovered programmed cell death that is associated with tumor
progression, prognosis, and treatment response. However, the potential roles of pyroptosis …

Abstract Background N6-methyladenosine (m6A) modification, the most abundant internal
methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing. As the …

In the last two decades, an increasing amount of studies have investigated the use of
components based on carbon-(nano) materials in the engineering of neural interfaces, to …

A DNA sequence is the hard copy of the human genome and it is a driving force in
determining the physiological processes in an organism. Concurrently, the chemical …

Single-cell RNA sequencing (scRNA-seq) has highlighted the important role of intercellular
heterogeneity in phenotype variability in both health and disease. However, current scRNA …