Intimal hyperplasia (IH) occurs in a considerable number of cases of blood vessel
reconstruction by stenting or balloon angioplasty, venous bypass grafting, and arteriovenous …

The unfolded protein response (UPR) is a highly conserved molecular machinery, which
protects the cells against a diverse variety of stimuli. Activation of this element has been …

Aims Gut microbiota and their generated metabolites impact the host vascular phenotype.
The metaorganismal metabolite trimethylamine N-oxide (TMAO) is both associated with …

Objective: Vascular smooth muscle cells (SMCs) dedifferentiate and initiate expression of
macrophage markers with cholesterol exposure. This phenotypic switching is dependent on …

Background: Vascular smooth muscle cells (SMCs) undergo complex phenotypic
modulation with atherosclerotic plaque formation in hyperlipidemic mice, which is …

Atherosclerosis, a chronic inflammatory disease of vascular wall, is a progressive
pathophysiological process with lipids oxidation/depositing initiation and innate/adaptive …

Olanzapine (OLZ) is a widely prescribed antipsychotic drug with a relatively ideal effect in
the treatment of schizophrenia (SCZ). However, its severe metabolic side effects often …

Highlights•The application of nanomaterials to the treatment of cardiovascular and other
disorders has lagged the development of materials for use in oncology.•The inclusion of cell …

Abdominal aortic aneurysm (AAA) is a progressive aortic dilatation, causing∼ 80% mortality
upon rupture. Currently, there is no approved drug therapy for AAA. Surgical repairs are …

Cell‐based nanotherapy holds great potential to transform diagnosis and treatment patterns
for human diseases, especially for cardiovascular diseases (CVDs). Surface coating with …