Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …

In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …

The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …

In its 33 years, ADDR has published regularly on the po5tential of oral delivery of biologics
especially peptides and proteins. In the intervening period, analysis of the preclinical and …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the recent
outbreak of coronavirus 2019 (COVID-19). Although nearly two decades have passed since …

This study investigated the effect of nanoparticle size (50 and 100 nm) and surface charge
on their interaction with Caco-2 monolayers as a model of the intestinal epithelium, including …

Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …

The oral application of pharmaceuticals is unarguably the most convenient method of
application. Especially for protein-or peptide-based drugs, however, the effectiveness is …

Oral drug administration is one of the most preferred and simplest routes among both
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …

Introduction: Many therapeutics are limited to parenteral administration. Oral administration
is a desirable alternative because of the convenience and increased compliance by …