[HTML][HTML] Skeletal muscle aging: influence of oxidative stress and physical exercise

MJ Gomes, PF Martinez, LU Pagan, RL Damatto… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Skeletal muscle abnormalities are responsible for significant disability in the elderly.
Sarcopenia is the main alteration occurring during senescence and a key public health …

The role of oxidative stress in the aging heart

LU Pagan, MJ Gomes, M Gatto, GAF Mota, K Okoshi… - Antioxidants, 2022 - mdpi.com
Medical advances and the availability of diagnostic tools have considerably increased life
expectancy and, consequently, the elderly segment of the world population. As age is a …

Mood disorders in the elderly: prevalence, functional impact, and management challenges

LCL Valiengo, F Stella, OV Forlenza - … disease and treatment, 2016 - Taylor & Francis
Despite the lower prevalence of severe mood disorders in the elderly as compared to
younger adults, late-life depression and bipolar disorder (BD) are more strongly associated …

[HTML][HTML] Cardiac cachexia: perspectives for prevention and treatment

MP Okoshi, RV Capalbo, FG Romeiro… - Arquivos brasileiros de …, 2016 - SciELO Brasil
Cachexia is a prevalent pathological condition associated with chronic heart failure. Its
occurrence predicts increased morbidity and mortality independent of important clinical …

Skeletal muscle fiber type in hypoxia: adaptation to high-altitude exposure and under conditions of pathological hypoxia

T Chaillou - Frontiers in physiology, 2018 - frontiersin.org
Skeletal muscle is able to modify its size, and its metabolic/contractile properties in response
to a variety of stimuli, such as mechanical stress, neuronal activity, metabolic and hormonal …

[HTML][HTML] Long-term low intensity physical exercise attenuates heart failure development in aging spontaneously hypertensive rats

LU Pagan, RL Damatto, MDM Cezar… - Cellular physiology and …, 2015 - karger.com
Background: Physical exercise is a strategy to control hypertension and attenuate pressure
overload-induced cardiac remodeling. The influence of exercise on cardiac remodeling …

Effects of aerobic and resistance exercise on cardiac remodelling and skeletal muscle oxidative stress of infarcted rats

MJ Gomes, LU Pagan, ARR Lima… - Journal of cellular …, 2020 - Wiley Online Library
We compared the influence of aerobic and resistance exercise on cardiac remodelling,
physical capacity and skeletal muscle oxidative stress in rats with MI‐induced heart failure …

Beneficial effects of physical exercise on functional capacity and skeletal muscle oxidative stress in rats with aortic stenosis‐induced heart failure

MJ Gomes, PF Martinez, DHS Campos… - Oxidative medicine …, 2016 - Wiley Online Library
Objective. We evaluated the influence of exercise on functional capacity, cardiac
remodeling, and skeletal muscle oxidative stress, MAPK, and NF‐κB pathway in rats with …

[HTML][HTML] High-fat diet promotes cardiac remodeling in an experimental model of obesity

F Martins, DHS Campos, LU Pagan… - Arquivos brasileiros de …, 2015 - SciELO Brasil
Background: Although nutritional, metabolic and cardiovascular abnormalities are
commonly seen in experimental studies of obesity, it is uncertain whether these effects result …

Low intensity physical exercise attenuates cardiac remodeling and myocardial oxidative stress and dysfunction in diabetic rats

C Gimenes, R Gimenes, CM Rosa… - Journal of diabetes …, 2015 - Wiley Online Library
We evaluated the effects of a low intensity aerobic exercise protocol on cardiac remodeling
and myocardial function in diabetic rats. Wistar rats were assigned into four groups …