Monocytes and macrophages as viral targets and reservoirs

E Nikitina, I Larionova, E Choinzonov… - International journal of …, 2018 - mdpi.com
Viruses manipulate cell biology to utilize monocytes/macrophages as vessels for
dissemination, long-term persistence within tissues and virus replication. Viruses enter cells …

Sustained virologic response to antiviral therapy for chronic hepatitis C virus infection: a cure and so much more

BL Pearlman, N Traub - Clinical infectious diseases, 2011 - academic.oup.com
Sustained virologic response (SVR) is defined as aviremia 24 weeks after completion of
antiviral therapy for chronic hepatitis C virus (HCV) infection. In analyses of SVR durability …

[PDF][PDF] Directed differentiation of human embryonic stem cells into functional hepatic cells

J Cai, Y Zhao, Y Liu, F Ye, Z Song, H Qin, S Meng… - …, 2007 - Wiley Online Library
The differentiation capacity of human embryonic stem cells (hESCs) holds great promise for
therapeutic applications. We report a novel three‐stage method to efficiently direct the …

A sustained virologic response is durable in patients with chronic hepatitis C treated with peginterferon alfa-2a and ribavirin

MG Swain, MY Lai, ML Shiffman, WGE Cooksley… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS:: A sustained virologic response (SVR) to therapy for hepatitis C
virus (HCV) infection is defined as the inability to detect HCV RNA 24 weeks after …

Eradication of hepatitis C virus in patients successfully treated for chronic hepatitis C

S Maylin, M Martinot–Peignoux, R Moucari, N Boyer… - Gastroenterology, 2008 - Elsevier
Background & Aims: It is unclear whether hepatitis C virus (HCV) is eradicated in patients
with chronic hepatitis C who achieved a sustained virologic response (SVR). Methods: In …

Flying under the radar: the immunobiology of hepatitis C

LB Dustin, CM Rice - Annu. Rev. Immunol., 2007 - annualreviews.org
The hepatitis C virus (HCV) is a remarkably successful pathogen, establishing persistent
infection in more than two-thirds of those who contract it. Its success is related to its abilities …

Molecular diagnostics of hepatitis C virus infection: a systematic review

JD Scott, DR Gretch - Jama, 2007 - jamanetwork.com
ContextHepatitis C virus (HCV) is a common blood-borne pathogen that relies heavily on
nucleic acid testing for confirmation of infection. Nucleic acid tests are invaluable for the …

[PDF][PDF] Cell culture–produced hepatitis C virus does not infect peripheral blood mononuclear cells

S Marukian, CT Jones, L Andrus, MJ Evans… - …, 2008 - Wiley Online Library
Hepatitis C virus (HCV) replicates primarily in the liver, but HCV RNA has been observed in
association with other tissues and cells including B and T lymphocytes, monocytes, and …

[PDF][PDF] Extrahepatic replication of HCV: insights into clinical manifestations and biological consequences

JT Blackard, N Kemmer, KE Sherman - Hepatology, 2006 - Wiley Online Library
An estimated 170 million persons are infected with the hepatitis C virus (HCV) worldwide.
While hepatocytes are the major site of infection, a broad clinical spectrum of extrahepatic …

Preparation, characterization, and dye removal study of activated carbon prepared from palm kernel shell

JR García, U Sedran, MAA Zaini, ZA Zakaria - Environmental Science and …, 2018 - Springer
Palm oil mill wastes (palm kernel shell (PKS)) were used to prepare activated carbons,
which were tested in the removal of colorants from water. The adsorbents were prepared by …