The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

In the recent years, both the prescriptions of serum 25 (OH) D levels assay, and vitamin D
supplementation are constantly increasing, as well as the costs to be incurred relating to …

Background Experimental and epidemiological studies suggest a protective role for vitamin
D in colorectal carcinogenesis, but evidence is inconclusive. Circulating 25-hydroxyvitamin …

The main role of vitamin D is regulating bone metabolism and calcium and phosphorus
homeostasis. Over the past few decades, the importance of vitamin D in non-skeletal actions …

The vitamin D receptor is expressed in multiple cells of the body (other than osteoblasts),
including beta cells and cells involved in immune modulation (such as mononuclear cells …

There has been substantial enthusiasm recently regarding the potential role of vitamin D in
the primary and secondary prevention of cancer. Laboratory studies demonstrate a range of …

Sun exposure is a major environmental risk factor for skin cancers and is also an important
source of vitamin D. However, while experimental evidence suggests that vitamin D may …

Observational studies from all over the world continue to find high prevalence rates of
vitamin D insufficiency and deficiency in many populations, including pregnant women …

Epidemiological evidence suggests that vitamin D deficiency is associated with increased
mortality, but it is unclear whether this is explained by reverse causation, and if there are …

Background Vitamin D has been suggested to prevent and improve the prognosis of several
cancers, including breast cancer. We have previously shown a U-shaped association …