Antioxidants and antioxidant methods: An updated overview

İ Gulcin - Archives of toxicology, 2020 - Springer
Antioxidants had a growing interest owing to their protective roles in food and
pharmaceutical products against oxidative deterioration and in the body and against …

Metal ions, metal chelators and metal chelating assay as antioxidant method

İ Gulcin, SH Alwasel - Processes, 2022 - mdpi.com
Heavy metals are essential for a wide range of biological processes, including the growth
and reproduction of cells, synthesis of biomolecules, many enzymatic reactions, and the …

[HTML][HTML] Synthesis and inhibition profiles of N-benzyl-and N-allyl aniline derivatives against carbonic anhydrase and acetylcholinesterase–A molecular docking study

I Mahmudov, Y Demir, Y Sert, Y Abdullayev… - Arabian Journal of …, 2022 - Elsevier
The alkyl and aryl derivatives of aniline are important starting materials in fine organic
synthesis. Allyl bromide and benzyl chloride were taken as substrates for the alkylation …

Advances in structure-based drug discovery of carbonic anhydrase inhibitors

CT Supuran - Expert opinion on drug discovery, 2017 - Taylor & Francis
Introduction: The enzyme carbonic anhydrase (CA, EC 4.2. 1.1) is found in numerous
organisms across the tree of life, with seven distinct classes known to date. CA inhibition can …

Comprehensive Metabolite Profiling of Cinnamon (Cinnamomum zeylanicum) Leaf Oil Using LC-HR/MS, GC/MS, and GC-FID: Determination of Antiglaucoma …

M Mutlu, Z Bingol, EM Uc, E Köksal, AC Goren… - Life, 2023 - mdpi.com
In this study, for the first time, the antioxidant and antidiabetic properties of the essential oil
from cinnamon (Cinnamomum zeylanicum) leaves were evaluated and investigated using …

Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: three for the price of one

CT Supuran, V Alterio, A Di Fiore… - Medicinal Research …, 2018 - Wiley Online Library
Human carbonic anhydrase (CA) IX is a tumor‐associated protein, since it is scarcely
present in normal tissues, but highly overexpressed in a large number of solid tumors, where …

Screening of carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzyme inhibition effects and antioxidant activity of coumestrol

L Durmaz, A Erturk, M Akyüz, L Polat Kose, EM Uc… - Molecules, 2022 - mdpi.com
Coumestrol (3, 9-dihydroxy-6-benzofuran [3, 2-c] chromenone) as a phytoestrogen and
polyphenolic compound is a member of the Coumestans family and is quite common in …

[HTML][HTML] Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS

P Taslimi, E Köksal, AC Gören, E Bursal, A Aras… - Arabian journal of …, 2020 - Elsevier
Many chronic diseases such as diabetes and Alzheimer's disease are related to the type
and quality of foods, which are consumed. Particularly, various plant origin products are …

Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and …

C Türkeş, M Arslan, Y Demir, L Cocaj, AR Nixha… - Bioorganic …, 2019 - Elsevier
The synthesis, characterization and biological evaluation of a series of novel N-substituted
phthalazine sulfonamide (5a-l) are disclosed. Phthalazines which are nitrogen-containing …

The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products

C Bayrak, P Taslimi, HS Karaman, I Gulcin… - Bioorganic chemistry, 2019 - Elsevier
Starting from vanillin, known four benzyl bromides with Br were synthesized. The first
synthesis of natural product 3, 4-dibromo-5-((methylsulfonyl) methyl) benzene-1, 2-diol (2) …