PURPOSE Evidence-based guidelines recommend cascade genetic counseling and testing
for hereditary cancer syndromes, providing relatives the opportunity for early detection and …

Purpose As whole-exome sequencing (WES) and whole-genome sequencing (WGS) move
into routine clinical practice, it is timely to review data that might inform the debate regarding …

Although acquiring information can provide numerous benefits, people often opt to remain
ignorant. We define information avoidance as any behavior designed to prevent or delay the …

We use novel data to study genetic testing among individuals at risk for Huntington disease
(HD), a hereditary disease with limited life expectancy. Although genetic testing is perfectly …

Purpose Several professional organizations recommend universal genetic assessment for
people with ovarian cancer as identifying pathogenic variants can affect treatment …

Purpose Women at high risk of breast cancer face the complex decision of whether to take
tamoxifen or raloxifene for breast cancer chemoprevention. We investigated what is known …

Patients who might benefit from genetic services may be denied access through failure to be
referred. To investigate the evidence on barriers to referral to genetic services, we …

To systematically review and meta-synthesise primary qualitative research findings
regarding family communication following genetic testing of cancer risk, in order to inform …

Background The use of genome-wide (whole genome or exome) sequencing for population-
based newborn screening presents an opportunity to detect and treat or prevent many more …

Fear of receiving bad news about one's health can lead people to avoid seeking out health
information that, ironically, may be crucial for health maintenance. Using a nationally …