Gut microbiota and diarrhea: an updated review

Y Li, S Xia, X Jiang, C Feng, S Gong, J Ma… - Frontiers in cellular …, 2021 - frontiersin.org
Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly
associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal …

The relationship between gut microbiota and inflammatory diseases: the role of macrophages

J Wang, WD Chen, YD Wang - Frontiers in microbiology, 2020 - frontiersin.org
Gut microbiota, an integral part of the human body, comprise bacteria, fungi, archaea, and
protozoa. There is consensus that the disruption of the gut microbiota (termed “gut …

[HTML][HTML] Pathogenic ubiquitination of GSDMB inhibits NK cell bactericidal functions

JM Hansen, MF de Jong, Q Wu, LS Zhang, DB Heisler… - Cell, 2021 - cell.com
Gasdermin B (GSDMB) belongs to a large family of pore-forming cytolysins that execute
inflammatory cell death programs. While genetic studies have linked GSDMB …

Mucispirillum schaedleri antagonizes Salmonella virulence to protect mice against colitis

S Herp, S Brugiroux, D Garzetti, D Ring, LM Jochum… - Cell host & …, 2019 - cell.com
The microbiota and the gastrointestinal mucus layer play a pivotal role in protection against
non-typhoidal Salmonella enterica serovar Typhimurium (S. Tm) colitis. Here, we analyzed …

Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium

S Brugiroux, M Beutler, C Pfann, D Garzetti… - Nature …, 2016 - nature.com
Protection against enteric infections, also termed colonization resistance, results from
mutualistic interactions of the host and its indigenous microbes. The gut microbiota of …

High-avidity IgA protects the intestine by enchaining growing bacteria

K Moor, M Diard, ME Sellin, B Felmy, SY Wotzka… - Nature, 2017 - nature.com
Vaccine-induced high-avidity IgA can protect against bacterial enteropathogens by directly
neutralizing virulence factors or by poorly defined mechanisms that physically impede …

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

CN Spaulding, RD Klein, S Ruer, AL Kau, HL Schreiber… - Nature, 2017 - nature.com
Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) affect 150
million people annually,. Despite effective antibiotic therapy, 30–50% of patients experience …

From in vitro to in vivo Models of Bacterial Biofilm-Related Infections

D Lebeaux, A Chauhan, O Rendueles, C Beloin - Pathogens, 2013 - mdpi.com
The influence of microorganisms growing as sessile communities in a large number of
human infections has been extensively studied and recognized for 30–40 years, therefore …

Commensal Akkermansia muciniphila Exacerbates Gut Inflammation in Salmonella Typhimurium-Infected Gnotobiotic Mice

BP Ganesh, R Klopfleisch, G Loh, M Blaut - PloS one, 2013 - journals.plos.org
Excessive mucin degradation by intestinal bacteria may contribute to inflammatory bowel
diseases because access of luminal antigens to the intestinal immune system is facilitated …

Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa

ME Sellin, AA Müller, B Felmy, T Dolowschiak… - Cell host & …, 2014 - cell.com
The gut mucosal epithelium separates the host from the microbiota, but enteropathogens
such as Salmonella Typhimurium (S. Tm) can invade and breach this barrier. Defenses …