Experimental evidence accumulated over decades has implicated epithelial–mesenchymal
plasticity (EMP), which collectively encompasses epithelial–mesenchymal transition and the …

Extracellular vesicles (EVs) including exosomes, microvesicles, oncosomes, and
microparticles have been associated with communicating anti-cancer drug-resistance. The …

Extracellular vesicles (EVs) mediate intercellular signaling and communication, allowing the
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …

Increasing evidence indicates that the ability of cancer cells to convey biological information
to recipient cells within the tumor microenvironment (TME) is crucial for tumor progression …

Cancer stem cells (CSCs) are a small group of cancer cells, which contribute to
tumorigenesis and cancer progression. Cancer cells undergoing epithelial-to-mesenchymal …

Extracellular vesicles (EVs), especially exosomes, are now well recognized as major ways
by which cancer cells interact with each other and stromal cells. The meaningful messages …

Prostate cancer (PCa) is the most common solid tumor in men. While patients with local PCa
have better prognostic survival, patients with metastatic PCa have relatively high mortality …

Complexity in mechanisms that drive cancer development and progression is exemplified by
the transforming growth factor β (TGF-β) signaling pathway, which suppresses early-stage …

Exosomes are nano-membrane vesicles that various cell types secrete during physiological
and pathophysiological conditions. By shuttling bioactive molecules such as nucleic acids …

Background Prostate cancer remains one of the deadliest neoplasms in developed
countries. Identification of new molecular markers that predict the onset and progression of …