Genetic contributions to anxiety disorders: where we are and where we are heading

H Ask, R Cheesman, ES Jami, DF Levey… - Psychological …, 2021 - cambridge.org
Anxiety disorders are among the most common psychiatric disorders worldwide. They often
onset early in life, with symptoms and consequences that can persist for decades. This …

Adolescent irritability: phenotypic associations and genetic links with depressed mood

A Stringaris, H Zavos, E Leibenluft… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective: Irritability has been proposed to underlie the developmental link between
oppositional problems and depression. Little is known, however, about the genetic and …

Sequential comorbidity of anxiety and depression in youth: Present knowledge and future directions

JL Schleider, ED Krause… - Current Psychiatry …, 2014 - ingentaconnect.com
Research suggests that a history of childhood anxiety correlates with and predicts
adolescent depression. The present review synthesizes current knowledge of relations …

A multivariate twin study of trait mindfulness, depressive symptoms, and anxiety sensitivity

MA Waszczuk, HMS Zavos, E Antonova… - Depression and …, 2015 - Wiley Online Library
Background Mindfulness‐based therapies have been shown to be effective in treating
depression and reducing cognitive biases. Anxiety sensitivity is one cognitive bias that may …

A multivariate genetic analysis of anxiety sensitivity, environmental sensitivity and reported life events in adolescents

AJ Peel, O Oginni, E Assary, G Krebs… - Journal of Child …, 2023 - Wiley Online Library
Background Despite being considered a measure of environmental risk, reported life events
are partly heritable. One mechanism that may contribute to this heritability is genetic …

[HTML][HTML] Familial co-aggregation and shared heritability between depression, anxiety, obesity and substance use

R Wang, H Snieder, CA Hartman - Translational Psychiatry, 2022 - nature.com
Depression, anxiety, obesity and substance use are heritable and often co-occur. However,
the mechanisms underlying this co-occurrence are not fully understood. We estimated their …

A longitudinal, genetically informative, study of associations between anxiety sensitivity, anxiety and depression

HMS Zavos, FV Rijsdijk, TC Eley - Behavior Genetics, 2012 - Springer
The current study sought to examine the direction of influences on longitudinal associations
between anxiety sensitivity, anxiety and depression. The continuity of genetic and …

Heritability of major depressive and comorbid anxiety disorders in multi‐generational families at high risk for depression

G Guffanti, MJ Gameroff, V Warner… - American Journal of …, 2016 - Wiley Online Library
Family studies have shown that MDD is highly transmittable but have not studied its
heritability. Twin studies show heritability of about 40% and do not include anxiety disorders …

Nature vs. nurture is nonsense: On the necessity of an integrated genetic, social, developmental, and personality psychology

FK Barlow - Australian journal of psychology, 2019 - Taylor & Francis
The field of behavioural genetics unambiguously demonstrates that heritable individual
differences exist and are important in explaining human behaviour. Despite this, some …

Attentional threat avoidance and familial risk are independently associated with childhood anxiety disorders

HM Brown, TA McAdams, KJ Lester… - Journal of Child …, 2013 - Wiley Online Library
Background: Twin studies in children reveal that familial aggregation of anxiety disorders is
due to both genetic and environmental factors. Cognitive biases for threat information are …