Radioprotection and radiomitigation: from the bench to clinical practice
The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …
Candidate gene biodosimetry markers of exposure to external ionizing radiation in human blood: A systematic review
Purpose To compile a list of genes that have been reported to be affected by external
ionizing radiation (IR) and to assess their performance as candidate biomarkers for …
ionizing radiation (IR) and to assess their performance as candidate biomarkers for …
FDXR is a biomarker of radiation exposure in vivo
G O'Brien, L Cruz-Garcia, M Majewski, J Grepl… - Scientific reports, 2018 - nature.com
Previous investigations in gene expression changes in blood after radiation exposure have
highlighted its potential to provide biomarkers of exposure. Here, FDXR transcriptional …
highlighted its potential to provide biomarkers of exposure. Here, FDXR transcriptional …
Early molecular markers for retrospective biodosimetry and prediction of acute health effects
M Abend, WF Blakely, P Ostheim… - Journal of …, 2022 - iopscience.iop.org
Radiation-induced biological changes occurring within hours and days after irradiation can
be potentially used for either exposure reconstruction (retrospective dosimetry) or the …
be potentially used for either exposure reconstruction (retrospective dosimetry) or the …
A review of radiation-induced alterations of multi-omic profiles, radiation injury biomarkers, and countermeasures
SK Shakyawar, NK Mishra… - Radiation …, 2023 - meridian.allenpress.com
Increasing utilization of nuclear power enhances the risks associated with industrial
accidents, occupational hazards, and the threat of nuclear terrorism. Exposure to ionizing …
accidents, occupational hazards, and the threat of nuclear terrorism. Exposure to ionizing …
Ionizing radiation exposure: hazards, prevention, and biomarker screening
H Mu, J Sun, L Li, J Yin, N Hu, W Zhao, D Ding… - … Science and Pollution …, 2018 - Springer
Radiation is a form of energy derived from a source that is propagated through material in
space. It consists of ionizing radiation or nonionizing radiation. Ionizing radiation is a feature …
space. It consists of ionizing radiation or nonionizing radiation. Ionizing radiation is a feature …
Comparison of gene expression response to neutron and x-ray irradiation using mouse blood
CG Broustas, Y Xu, AD Harken, G Garty, SA Amundson - BMC genomics, 2017 - Springer
Background In the event of an improvised nuclear device detonation, the prompt radiation
exposure would consist of photons plus a neutron component that would contribute to the …
exposure would consist of photons plus a neutron component that would contribute to the …
Insights into a critical role of the FOXO3a-FOXM1 axis in DNA damage response and genotoxic drug resistance
G Nestal de Moraes, L Bella, S Zona… - Current drug …, 2016 - ingentaconnect.com
FOXO3a and FOXM1 are two forkhead transcription factors with antagonistic roles in cancer
and DNA damage response. FOXO3a functions like a typical tumour suppressor, whereas …
and DNA damage response. FOXO3a functions like a typical tumour suppressor, whereas …
Two-miRNA–based finger-stick assay for estimation of absorbed ionizing radiation dose
Nuclear radiation and radioactive fallouts resulting from a nuclear weapon detonation or
reactor accidents could result in injuries affecting multiple sensitive organs, defined as acute …
reactor accidents could result in injuries affecting multiple sensitive organs, defined as acute …
Radiation-induced alternative transcription and splicing events and their applicability to practical biodosimetry
Accurate assessment of the individual exposure dose based on easily accessible samples
(eg blood) immediately following a radiological accident is crucial. We aimed at developing …
(eg blood) immediately following a radiological accident is crucial. We aimed at developing …