[HTML][HTML] Role of solvents in improvement of dissolution rate of drugs: crystal habit and crystal agglomeration

M Maghsoodi - Advanced pharmaceutical bulletin, 2015 - ncbi.nlm.nih.gov
Crystallization is often used for manufacturing drug substances. Advances of crystallization
have achieved control over drug identity and purity, but control over the physical form …

Quality by design guided development of polymeric nanospheres of terbinafine hydrochloride for topical treatment of onychomycosis using a nano-gel formulation

V Puri, A Froelich, P Shah, S Pringle, K Chen… - Pharmaceutics, 2022 - mdpi.com
Superficial fungal diseases of the skin and nails are an increasingly common occurrence
globally, requiring effective topical treatment to avoid systemic adverse effects. Polymeric …

Printing drugs onto nails for effective treatment of onychomycosis

TD Pollard, M Bonetti, A Day, S Gaisford, M Orlu… - Pharmaceutics, 2022 - mdpi.com
Inkjet printing (IJP) is an emerging technology for the precision dosing of medicines. We
report, for the first time, the printing of the antifungal drug terbinafine hydrochloride directly …

Polymorphism of anti-HIV drug efavirenz: investigations on thermodynamic and dissolution properties

C Fandaruff, GS Rauber, AM Araya-Sibaja… - Crystal growth & …, 2014 - ACS Publications
Polymorphs, cocrystals, solvates, and hydrates have been reported for efavirenz (EFV),
which is part of high activity antiretroviral therapy (HAART), and it is considered to be the …

New therapeutic system based on hydrogels for vaginal candidiasis management: formulation–characterization and in vitro evaluation based on vaginal irritation and …

MD Arpa, A Yoltaş, E Onay Tarlan… - Pharmaceutical …, 2020 - Taylor & Francis
The objective of the present research was to examine the possible usage of terbinafine
loaded hydrogels for vaginal application as part of vaginal candidiasis treatment. Vaginal …

Risperidone–Solid-state characterization and pharmaceutical compatibility using thermal and non-thermal techniques

JSP Daniel, IP Veronez, LL Rodrigues, MG Trevisan… - Thermochimica …, 2013 - Elsevier
A full solid-state characterization of risperidone was conducted using differential scanning
calorimetry (DSC), thermogravimetry (TG), powder X-ray diffraction (PXRD), Fourier …

Topical Delivery of Terbinafine HCL Using Nanogels: A New Approach to Superficial Fungal Infection Treatment

S Hassan, I Khalid, L Hussain, MT Imam, I Shahid - Gels, 2023 - mdpi.com
This study investigated pH-responsive Terbinafine HCL (TBH)-loaded nanogels as a new
approach to treating superficial fungal infections. Acrylic acid (AA) is a synthetic monomer …

Fabrication of Dissolvable Microneedle Patches Using an Innovative Laser-Cut Mould Design to Shortlist Potentially Transungual Delivery Systems: In Vitro …

E Albarahmieh, L AbuAmmouneh, Z Kaddoura… - AAPS …, 2019 - Springer
There has been a great interest towards transungual delivery systems due to limited drug
penetration for the treatment of nail diseases. More important, antifungal oral medicaments …

Novel First-Generation Dissolution Models to Investigate the Release and Uptake of Oral Lymphotropic Drug Products

M Yousef, C Park, NB Chacra, NM Davies… - AAPS …, 2024 - Springer
Conventional dissolution tests only assess the aqueous release of drugs to ensure quality
and performance, without indicating whether absorption occurs through the portal or the …

Terbinafine hydrochloride nanovesicular gel: In vitro characterization, ex vivo permeation and clinical investigation

SM AbdelSamie, AO Kamel, OA Sammour… - European Journal of …, 2016 - Elsevier
In this work, nanovesicular chitosan gels were prepared for dermal delivery of terbinafine
hydrochloride (TBN HCl). Ethosomes and vesicles containing different types of penetration …