The physiological role of α‐synuclein and its relationship to Parkinson's Disease
D Sulzer, RH Edwards - Journal of neurochemistry, 2019 - Wiley Online Library
The protein α‐synuclein has a central role in the pathogenesis of Parkinson's disease (PD).
In this review, we discuss recent results concerning its primary function, which appears to be …
In this review, we discuss recent results concerning its primary function, which appears to be …
BDNF and hippocampal synaptic plasticity
G Leal, CR Bramham, CB Duarte - Vitamins and hormones, 2017 - Elsevier
Brain-derived neurotrophic factor (BDNF) belongs to a family of small secreted proteins that
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …
[HTML][HTML] The physiology of regulated BDNF release
T Brigadski, V Leßmann - Cell and Tissue Research, 2020 - Springer
The neurotrophic factor BDNF is an important regulator for the development of brain circuits,
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …
Neurotrophin regulation of neural circuit development and function
H Park, M Poo - Nature Reviews Neuroscience, 2013 - nature.com
Brain-derived neurotrophic factor (BDNF)—a member of a small family of secreted proteins
that includes nerve growth factor, neurotrophin 3 and neurotrophin 4—has emerged as a …
that includes nerve growth factor, neurotrophin 3 and neurotrophin 4—has emerged as a …
Synaptic memory and CaMKII
RA Nicoll, H Schulman - Physiological reviews, 2023 - journals.physiology.org
Ca2+/calmodulin-dependent protein kinase II (CaMKII) and long-term potentiation (LTP)
were discovered within a decade of each other and have been inextricably intertwined ever …
were discovered within a decade of each other and have been inextricably intertwined ever …
Neurobiological after-effects of non-invasive brain stimulation
Background In recent years, many studies have evaluated the effects of noninvasive brain
stimulation (NIBS) techniques for the treatment of several neurological and psychiatric …
stimulation (NIBS) techniques for the treatment of several neurological and psychiatric …
[HTML][HTML] Lactate and BDNF: key mediators of exercise induced neuroplasticity?
P Müller, Y Duderstadt, V Lessmann… - Journal of Clinical …, 2020 - mdpi.com
Accumulating evidence from animal and human studies supports the notion that physical
exercise can enhance neuroplasticity and thus reduce the risk of several neurodegenerative …
exercise can enhance neuroplasticity and thus reduce the risk of several neurodegenerative …
BDNF function and intracellular signaling in neurons
T Numakawa, S Suzuki, E Kumamaru… - Histology and …, 2010 - digitum.um.es
Brain-derived neurotrophic factor (BDNF) and its receptor, TrkB, are broadly expressed in
thedeveloping and adult mammalian brain. BDNF/TrkB-stimulated intracellular signaling is …
thedeveloping and adult mammalian brain. BDNF/TrkB-stimulated intracellular signaling is …
[HTML][HTML] Pleiotropic effects of BDNF on the cerebellum and hippocampus: Implications for neurodevelopmental disorders
Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
mammalian brain, essential not only to the development of the central nervous system but …
mammalian brain, essential not only to the development of the central nervous system but …
Synaptic plasticity in depression: molecular, cellular and functional correlates
WN Marsden - Progress in Neuro-Psychopharmacology and …, 2013 - Elsevier
Synaptic plasticity confers environmental adaptability through modification of the
connectivity between neurons and neuronal circuits. This is achieved through changes to …
connectivity between neurons and neuronal circuits. This is achieved through changes to …