The reproducibility crisis in the age of digital medicine
A Stupple, D Singerman, LA Celi - NPJ digital medicine, 2019 - nature.com
If anyone doubts the explosive growth of interest in digital medicine, consider a recent
conference and workshop in Beijing, jointly organized by the People's Liberation Army …
conference and workshop in Beijing, jointly organized by the People's Liberation Army …
How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation
The clinical translation of promising products, technologies and interventions from the
disciplines of nanomedicine and cell therapy has been slow and inefficient. In part …
disciplines of nanomedicine and cell therapy has been slow and inefficient. In part …
Nextflow enables reproducible computational workflows
P Di Tommaso, M Chatzou, EW Floden, PP Barja… - Nature …, 2017 - nature.com
The increasing complexity of readouts for omics analyses goes hand-in-hand with concerns
about the reproducibility of experiments that analyze'big data'1, 2, 3. When analyzing very …
about the reproducibility of experiments that analyze'big data'1, 2, 3. When analyzing very …
AiiDA 1.0, a scalable computational infrastructure for automated reproducible workflows and data provenance
The ever-growing availability of computing power and the sustained development of
advanced computational methods have contributed much to recent scientific progress …
advanced computational methods have contributed much to recent scientific progress …
Why and how to account for sex and gender in brain and behavioral research
Long overlooked in neuroscience research, sex and gender are increasingly included as
key variables potentially impacting all levels of neurobehavioral analysis. Still, many …
key variables potentially impacting all levels of neurobehavioral analysis. Still, many …
Systematic integration of biomedical knowledge prioritizes drugs for repurposing
The ability to computationally predict whether a compound treats a disease would improve
the economy and success rate of drug approval. This study describes Project Rephetio to …
the economy and success rate of drug approval. This study describes Project Rephetio to …
The future of academic publishing
Academic publishing is the backbone of science dissemination––but is the current system fit
for purpose? We asked a diverse group of scientists to comment on the future of publishing …
for purpose? We asked a diverse group of scientists to comment on the future of publishing …
COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time
B Goldacre, H Drysdale, A Dale, I Milosevic, E Slade… - Trials, 2019 - Springer
Background Discrepancies between pre-specified and reported outcomes are an important
source of bias in trials. Despite legislation, guidelines and public commitments on correct …
source of bias in trials. Despite legislation, guidelines and public commitments on correct …
Contextualising harm in the framework of research misconduct. Findings from discourse analysis of scientific publications
This article reports on research, which deals with dimensions of harm resulting from
research misconduct, in articles published in scientific journals. An appropriate sample of …
research misconduct, in articles published in scientific journals. An appropriate sample of …
[图书][B] Reproducibility and replicability in science
National Academies of Sciences, Policy, Global Affairs… - 2019 - books.google.com
One of the pathways by which the scientific community confirms the validity of a new
scientific discovery is by repeating the research that produced it. When a scientific effort fails …
scientific discovery is by repeating the research that produced it. When a scientific effort fails …