Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

[HTML][HTML] Seronegative antiphospholipid syndrome: refining the value of “non-criteria” antibodies for diagnosis and clinical management

P Pignatelli, E Ettorre, D Menichelli, A Pani, F Violi… - …, 2020 - ncbi.nlm.nih.gov
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by
arterial and venous thrombotic manifestations and/or pregnancy-related complications in …

[HTML][HTML] Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised …

H Cohen, BJ Hunt, M Efthymiou… - The Lancet …, 2016 - thelancet.com
Background Rivaroxaban is established for the treatment and secondary prevention of
venous thromboembolism, but whether it is useful in patients with antiphospholipid …

Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the …

S Yalavarthi, TJ Gould, AN Rao, LF Mazza… - Arthritis & …, 2015 - Wiley Online Library
Objective Antiphospholipid antibodies (aPL), especially those targeting β2‐glycoprotein I
(β2GPI), are well known to activate endothelial cells, monocytes, and platelets, with …

[HTML][HTML] Management and treatment of glomerular diseases (part 2): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies …

BH Rovin, DJ Caster, DC Cattran, KL Gibson… - Kidney international, 2019 - Elsevier
In November 2017, the Kidney Disease: Improving Global Outcomes (KDIGO) initiative
brought a diverse panel of experts in glomerular diseases together to discuss the 2012 …

[HTML][HTML] Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome

RA Ali, AA Gandhi, H Meng, S Yalavarthi… - Nature …, 2019 - nature.com
Potentiation of neutrophil extracellular trap (NET) release is one mechanism by which
antiphospholipid antibodies (aPL Abs) effect thrombotic events in patients with …

The relevance of “non-criteria” clinical manifestations of antiphospholipid syndrome: 14th international congress on antiphospholipid antibodies technical task force …

MM Abreu, A Danowski, DG Wahl, MC Amigo… - Autoimmunity …, 2015 - Elsevier
The purpose of this task force was to critically analyze nine non-criteria manifestations of
APS to support their inclusion as APS classification criteria. The Task Force Members …

14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends

ML Bertolaccini, O Amengual, L Andreoli, T Atsumi… - Autoimmunity …, 2014 - Elsevier
Current classification criteria for definite Antiphospholipid Syndrome (APS) require the use
of three laboratory assays to detect antiphospholipid antibodies (aCL, anti-β2GPI and LA) in …

The diagnosis and clinical management of the neuropsychiatric manifestations of lupus

M Govoni, A Bortoluzzi, M Padovan, E Silvagni… - Journal of …, 2016 - Elsevier
Neuropsychiatric (NP) involvement in Systemic Lupus Erythematosus (SLE), can be a
severe and troubling manifestation of the disease that heavily impacts patient's health …

Hydroxychloroquine: An old drug with new relevance.

EA Shippey, VD Wagler, AN Collamer - Cleveland Clinic journal of …, 2018 - europepmc.org
Hydroxychloroquine is an immunomodulatory drug that has been used for 60 years to treat
malaria and autoimmune diseases such as systemic lupus erythematosus and inflammatory …