Cortical spreading depression (CSD) and depolarization waves are associated with
dramatic failure of brain ion homeostasis, efflux of excitatory amino acids from nerve cells …

Many advances have been achieved in terms of understanding the molecular and cellular
mechanisms of ischemic stroke. But thus far, clinically effective neuroprotectants remain …

Migraine—an episodic headache—affects more than 10% of the general population.
Despite recent progress, drug therapy for preventing and treating migraine remains …

Progressive ischaemic damage in animals is associated with spreading mass
depolarizations of neurons and astrocytes, detected as spreading negative slow voltage …

The use of pigs in neuroscience research has increased in the past decade, which has seen
broader recognition of the potential of pigs as an animal for experimental modeling of …

Electrocorticographic (ECoG) activity was recorded for up to 129 h from 12 acutely brain-
injured human patients using six platinum electrodes placed near foci of damaged cortical …

Background and Purpose—Cortical spreading depression (CSD) has been much studied
experimentally but never demonstrated unequivocally in human neocortex by direct …

Migraine is a very common disorder occurring in 20% of women and 6% of men. Central
neuronal hyperexcitability is proposed to be the putative basis for the physiological …

We investigate and characterize the magnetoencephalographic waveforms from patients
during spontaneous and visually induced migraine aura. Direct current neuromagnetic fields …

Both EEG and magnetoencephalogram (MEG), with a time resolution of 1 ms or less,
provide unique neurophysiologic data not obtainable by other neuroimaging techniques …