[HTML][HTML] Human organoids in basic research and clinical applications
Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …
[HTML][HTML] Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration
Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …
attention as a way to better mimic the complex interactions between individual cells and the …
[HTML][HTML] Progress in multicellular human cardiac organoids for clinical applications
Advances in self-organizing cardiac organoids to recapitulate human cardiogenesis have
provided a powerful tool for unveiling human cardiac development, studying cardiovascular …
provided a powerful tool for unveiling human cardiac development, studying cardiovascular …
[HTML][HTML] Future regenerative medicine developments and their therapeutic applications
Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …
Engineered organoids for biomedical applications
As miniaturized and simplified stem cell-derived 3D organ-like structures, organoids are
rapidly emerging as powerful tools for biomedical applications. With their potential for …
rapidly emerging as powerful tools for biomedical applications. With their potential for …
[HTML][HTML] Three-dimensional cell cultures: the bridge between in vitro and in vivo models
O Urzì, R Gasparro, E Costanzo, A De Luca… - International Journal of …, 2023 - mdpi.com
Although historically, the traditional bidimensional in vitro cell system has been widely used
in research, providing much fundamental information regarding cellular functions and …
in research, providing much fundamental information regarding cellular functions and …
Chitosan 3D cell culture system promotes naïve-like features of human induced pluripotent stem cells: A novel tool to sustain pluripotency and facilitate differentiation
A simplified and cost-effective culture system for maintaining the pluripotency of human
induced pluripotent stem cells (hiPSCs) is crucial for stem cell applications. Although …
induced pluripotent stem cells (hiPSCs) is crucial for stem cell applications. Although …
[HTML][HTML] Human cardiac organoids for modeling genetic cardiomyopathy
M Filippo Buono, L von Boehmer, J Strang… - Cells, 2020 - mdpi.com
Genetic cardiomyopathies are characterized by changes in the function and structure of the
myocardium. The development of a novel in vitro model could help to better emulate healthy …
myocardium. The development of a novel in vitro model could help to better emulate healthy …
Cardiac organoid: Multiple construction approaches and potential applications
The human cardiac organoid (hCO) is three-dimensional tissue model that is similar to an in
vivo organ and has great potential on heart development biology, disease modeling, drug …
vivo organ and has great potential on heart development biology, disease modeling, drug …
[HTML][HTML] Evolution of organoid technology: Lessons learnt in Co-Culture systems from developmental biology
In recent years, the development of 3D organoids has opened new avenues of investigation
into development, physiology, and regenerative medicine. Organoid formation and the …
into development, physiology, and regenerative medicine. Organoid formation and the …