In vitro models for neurogenesis

H Azari, BA Reynolds - Cold Spring Harbor perspectives …, 2016 - cshperspectives.cshlp.org
The process of generating new neurons of different phenotype and function from
undifferentiated stem and progenitor cells starts at very early stages of development and …

Repetitive transcranial magnetic stimulation improves neurological function and promotes the anti-inflammatory polarization of microglia in ischemic rats

J Luo, Y Feng, M Li, M Yin, F Qin, X Hu - Frontiers in cellular …, 2022 - frontiersin.org
Ischemic stroke (IS) is a severe neurological disease that is difficult to recovery. Previous
studies have shown that repetitive transcranial magnetic stimulation (rTMS) is a promising …

Critical points for optimizing long-term culture and neural differentiation capacity of rodent and human neural stem cells to facilitate translation into clinical settings

K Radoszkiewicz, V Hribljan, J Isakovic, D Mitrecic… - Experimental …, 2023 - Elsevier
Despite several decades of research on the nature and functional properties of neural stem
cells, which brought great advances in regenerative medicine, there is still a plethora of …

The RNA binding protein IMP2 preserves glioblastoma stem cells by preventing let-7 target gene silencing

N Degrauwe, TB Schlumpf, M Janiszewska, P Martin… - Cell reports, 2016 - cell.com
Cancer stem cells (CSCs) can drive tumor growth, and their maintenance may rely on post-
transcriptional regulation of gene expression, including that mediated by microRNAs …

Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes

CP Yang, X Li, Y Wu, Q Shen, Y Zeng, Q Xiong… - Nature …, 2018 - nature.com
Recent genome-wide association studies (GWAS) have identified multiple risk loci that show
strong associations with schizophrenia. However, pinpointing the potential causal genes at …

Neural stem cell protects aged rat brain from ischemia–reperfusion injury through neurogenesis and angiogenesis

Y Tang, J Wang, X Lin, L Wang… - Journal of cerebral …, 2014 - journals.sagepub.com
Neural stem cells (NSCs) show therapeutic potential for ischemia in young-adult animals.
However, the effect of aging on NSC therapy is largely unknown. In this work, NSCs were …

Curcumin as a double-edged sword for stem cells: dose, time and cell type-specific responses to curcumin

F Attari, M Zahmatkesh, H Aligholi, SE Mehr… - DARU Journal of …, 2015 - Springer
Background The beneficial effects of curcumin which includes its antioxidant, anti-
inflammatory and cancer chemo-preventive properties have been identified. Little …

Biomimetic hydrogels direct spinal progenitor cell differentiation and promote functional recovery after spinal cord injury

SA Geissler, AL Sabin, RR Besser… - Journal of neural …, 2018 - iopscience.iop.org
Objective. Demyelination that results from disease or traumatic injury, such as spinal cord
injury (SCI), can have a devastating effect on neural function and recovery. Many …

Enhancing neural stem cell response to SDF-1α gradients through hyaluronic acid-laminin hydrogels

CP Addington, JM Heffernan, CS Millar-Haskell… - Biomaterials, 2015 - Elsevier
Traumatic brain injury (TBI) initiates an expansive biochemical insult that is largely
responsible for the long-term dysfunction associated with TBI; however, current clinical …

Hyaluronic acid-laminin hydrogels increase neural stem cell transplant retention and migratory response to SDF-1α

CP Addington, S Dharmawaj, JM Heffernan… - Matrix Biology, 2017 - Elsevier
The chemokine SDF-1α plays a critical role in mediating stem cell response to injury and
disease and has specifically been shown to mobilize neural progenitor/stem cells (NPSCs) …